Chapter 44, Problem 2Q

Summary Introduction

To review:

The evidence that suggests that the Channelrhodopsin-2 (ChR2)expressing hypocretin (Hcrt) neurons get directly affected by light stimulation.

Introduction:

The ChR2 protein gets stimulated upon getting exposed to the light. Hypocretin neurons are present in the lateral hypothalamus and are involved in the awakening condition of the animal. The effect of light is checked by flashing a beam of light on the ChR2 expressing hcrt cells.