Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 24.1, Problem 2COMQ

The purpose of a ChIP-chip assay is to determine

a. the expression levels of particular genes in the genome.

b. the sites in a genome where a particular protein binds.

c. the amount of a specific protein that is made in a given cell type.

d. any of the above.

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Site-directed mutagenesis can be used to: a.   treat diseases by gene therapy.   b. make single residue mutation of a protein. c. make human insulin for treatment of diabetes. d. determine protein structures. e. determine DNA sequencing
The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides CRISPR, techniques for integrating DNA into the genome do not target that DNA to a particular genomic location and thus different cells end up with the DNA sequence in different positions. B.     The same gene integrated into different locations in the genome will be expressed differently.  Why?
When using gene therapy to treat an hereditary disease, the idea is to: A. Introduce the correct gene into the patient's DNA B. Inject the patient with a specific protein to cure the disease. C. Blood transfusions from healthy individuals. D. ntroduce mRNA molecules with the correct genetic information to the patient. E. Introduce a virus to the patient that will specifically destroy mutated cells.
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