Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 24, Problem 11EQ
Summary Introduction

To review:

The use of pattern recognition, sequence recognition or both to identify the following:

A. The presence of P element in the Drosophila.

B. The presence of stop codon in a stretch of DNA (deoxyribonucleic acid).

C. The presence of an inverted sequence in one segment with respect to the other.

D. The presence of one or more genes in a long stretch of bacterial DNA.

Introduction:

With the advancement of technology, the gene of interest can be easily searched in a genome that has been newly sequenced, in case the sequence of gene is known. Using this approach, genes with known functions can be identified in the newly sequenced genome, thus helping in the genome annotation.

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a molecular geneticist hopes to find a gene in human liver cells that codes for an important blood-clotting protein. he knows that the nucleotide sequence of a small part of the gene is gtggactgaca. briefly explain how to obtain the desired gene answer
Consider the following portion of mRNA produced by the normal order of DNA nucleotides: 5’ – CUU AAA CCA GUU – 3’ a. What is the template DNA sequence that was used to synthesize this portion of mRNA? b. What is the amino acid order produced from this mRNA? c. Write the amino acid sequence if a mutation changes CUU to CAU. Is this likely to affect protein function?
Consider the following gene with their respective introns and exons   5’ – TCATGCATTTTGCGCGGGAAATAGCTCA – 3’ 3’ – AGTACGTAAAACGCGCCCTTTATCGAGT – 5’ Using the bottom as a template strand, create: A. A primary mRNA transcript B. A processed mRNA transcriptC. Highlight where your START and STOP codons are in your processed transcript (if there are any).  D. The resulting protein sequence
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY