Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 23, Problem 41P
Interpretation Introduction
Interpretation:
Degradation signals and protein-protein interactions are generally present in protein regions. The explanation for the coexistence of these two functions in the same domain can be useful.
Concept introduction:
Protein-protein interaction networks or PPIN are the mathematical representations of the physical relations present between the proteins of the cell. These relations are definite and occur between demarcated binding regions in the proteins. They have a specific function.
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proteins. Which of the following will tell you whether a protein would be found in the lumen of the ER?
A. You run a hydropathy plot an look for hydrophobic peaks that span 20-30 amino acids
B. You isolate microsomes and see whether the proteins are inserted into the membrane of the microsome
C. You run a hydropathy plot an look for a lack of hydrophobic peaks that span 20-30 amino acids
O D. You do in vitro translation of each protein in the presence or absence of microsomes and look to see whether there is a size change in the presence
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Degradation signals are commonly located in protein regions that also facilitate protein–protein interactions. Explain why this coexistence of two functions in the same domain might be useful.
Need help. Plz explain briefly
Describe in detail with the aid of diagrams the use of chemical shift perturbation mapping to identify ligand binding sites on a protein.
Chapter 23 Solutions
Biochemistry
Ch. 23 - Prob. 1PCh. 23 - Prob. 2PCh. 23 - Prob. 3PCh. 23 - Prob. 4PCh. 23 - Prob. 5PCh. 23 - Prob. 6PCh. 23 - Prob. 7PCh. 23 - Prob. 8PCh. 23 - Prob. 9PCh. 23 - Prob. 10P
Ch. 23 - Prob. 11PCh. 23 - Prob. 12PCh. 23 - Prob. 13PCh. 23 - Prob. 14PCh. 23 - Prob. 15PCh. 23 - Prob. 16PCh. 23 - Prob. 17PCh. 23 - Prob. 18PCh. 23 - Prob. 19PCh. 23 - Prob. 20PCh. 23 - Prob. 21PCh. 23 - Prob. 22PCh. 23 - Prob. 23PCh. 23 - Prob. 24PCh. 23 - Prob. 25PCh. 23 - Prob. 26PCh. 23 - Prob. 27PCh. 23 - Prob. 28PCh. 23 - Prob. 29PCh. 23 - Prob. 30PCh. 23 - Prob. 31PCh. 23 - Prob. 32PCh. 23 - Prob. 33PCh. 23 - Prob. 34PCh. 23 - Prob. 35PCh. 23 - Prob. 36PCh. 23 - Prob. 37PCh. 23 - Prob. 38PCh. 23 - Prob. 39PCh. 23 - Prob. 40PCh. 23 - Prob. 41PCh. 23 - Prob. 42PCh. 23 - Prob. 43PCh. 23 - Prob. 44PCh. 23 - Prob. 45PCh. 23 - Prob. 46PCh. 23 - Prob. 47PCh. 23 - Prob. 48PCh. 23 - Prob. 49P
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