Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 23, Problem 12P
Interpretation Introduction
Interpretation:
The name of alpha-ketoacid which is produced by the transamination of the given amino acids: Alanine, Leucine, Aspartate, Phenylalanine, Glutamate, and Tyrosine Should be determined.
Concept introduction:
Transamination is also known as an amino transfer. It is a
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Accepting. Which of the following compounds readily accepts amino
groups from amino acids?
a. Glutamine
b. Isocitrate
c. Malate
d. a-Ketoglutarate-Ketoglutarate
. A nervous polecat. Pyrrolysine (Pyl, O) and Selenocysteine (Sec, U) are two uncommon amino acids.
Knowing that these amino acids exists, translate the following amino acid sequence into one – letter code: Thr
– Trp – Ile – Thr – Cys – His – Tyr – Leu – Ile – Thr – Thr – Ile – Glu – Phe – Glu – Arg – Arg – Glu – Thr – Ala
– Arg – Glu – Asn – Thr – Tyr – Pyl – Sec – Met – Ala – Leu – Phe – Pyl – Tyr.
Help filling in the blanks:
Pyridoxal phosphate, PLP, is produced from pyridoxine or vitamin B6. PLP is considered a/an [1C/2C/acyl/amino/carboxyl] carrier. In transaminases, PLP forms a [Schiff base/acetal/phosphoanhydride/condensation] with an amino acid and causes the [a- amino/a-carbon/a-carboxyl] to become [electrophilic/nucleophilic] allowing replacement of the amino group on the amino acid with a ketone. PLP is also used by several other enzymes that work on amino acids because in forming a covalent bond with amino acids it provides for an opportunity for nucleophilic attack and because PLP is conjugated, the cofactor is able to [delocalize/transfer/reduce/stabilize] pi electrons in the substrate and thus [stabilize/delocalize/transfer/reduce] the transition state of the reaction.
Production of citrulline occurs in the [cytosol/mitochondrial matrix] while the rest of the urea cycle occurs in the [cytosol/mitochondrial matrix]. Urea is produced in the…
Chapter 23 Solutions
Biochemistry
Ch. 23 - Prob. 1PCh. 23 - Prob. 2PCh. 23 - Prob. 3PCh. 23 - Prob. 4PCh. 23 - Prob. 5PCh. 23 - Prob. 6PCh. 23 - Prob. 7PCh. 23 - Prob. 8PCh. 23 - Prob. 9PCh. 23 - Prob. 10P
Ch. 23 - Prob. 11PCh. 23 - Prob. 12PCh. 23 - Prob. 13PCh. 23 - Prob. 14PCh. 23 - Prob. 15PCh. 23 - Prob. 16PCh. 23 - Prob. 17PCh. 23 - Prob. 18PCh. 23 - Prob. 19PCh. 23 - Prob. 20PCh. 23 - Prob. 21PCh. 23 - Prob. 22PCh. 23 - Prob. 23PCh. 23 - Prob. 24PCh. 23 - Prob. 25PCh. 23 - Prob. 26PCh. 23 - Prob. 27PCh. 23 - Prob. 28PCh. 23 - Prob. 29PCh. 23 - Prob. 30PCh. 23 - Prob. 31PCh. 23 - Prob. 32PCh. 23 - Prob. 33PCh. 23 - Prob. 34PCh. 23 - Prob. 35PCh. 23 - Prob. 36PCh. 23 - Prob. 37PCh. 23 - Prob. 38PCh. 23 - Prob. 39PCh. 23 - Prob. 40PCh. 23 - Prob. 41PCh. 23 - Prob. 42PCh. 23 - Prob. 43PCh. 23 - Prob. 44PCh. 23 - Prob. 45PCh. 23 - Prob. 46PCh. 23 - Prob. 47PCh. 23 - Prob. 48PCh. 23 - Prob. 49P
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