The necessity to link chain A and B with β-galactosidase and the separation of the chains after the synthesis of the fusion protein in Escherichia coli . Introduction: Insulin is the first genetically engineered drug. Human insulin is responsible for regulating the uptake of glucose into fat and muscle cells. The beta pancreatic cells are responsible for producing insulin. The loss of these cells results in inadequate production of insulin.

Question

A gene contains the sequence CGCATACGGTAC that results in the amino acid sequence arg-ile-arq- tyr. A mutation in this gene has a G inserted after the second C in the strand. How will this mutation affect the phenotype? A)This will affect the phenotype because although most of the protein will be identical, the first amino acid will be different. B)This will not affect the phenotype because only the second amino acid is different from the original protein. C)This will not affect the phenotype because the protein will be identical to the original protein. D)This will affect the phenotype because all of the amino acids after the first one will be different from the original protein.

Answer 1

Question

Chapter 22, Problem 3EQ

Summary Introduction

To review:

The necessity to link chain A and B with β-galactosidase and the separation of the chains after the synthesis of the fusion protein in Escherichia coli.

Introduction:

Insulin is the first genetically engineered drug. Human insulin is responsible for regulating the uptake of glucose into fat and muscle cells. The beta pancreatic cells are responsible for producing insulin. The loss of these cells results in inadequate production of insulin.

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