Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 22.1, Problem 2COMQ
Summary Introduction

Introduction:

Insulin is a hormone composed of two polypeptide chain A and B, which are joined by disulfide bonds. The synthetic insulin is used by many diabetic patients to regulate their blood sugar levels. The production of human insulin in the Escherichia coli (E. coli) is a significant discovery in biotechnology. The chains of insulin are produced in the bacterial cell and extracted out to form active insulin.

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Mature human insulin is synthesized from a single Gene but contains two polypeptide chains (A and B) linked by disulfide bonds. Which of the following statements about the A and B chains provides the best explanation for the production of human insulin? a. They are identical and combine to form the mature insulin b. They are produced by proteolytic processing of a single translation product d. c. They are the products of alternative translation-initiation sites on a single mRNA They are the product of a separate A- and B-chain mRNA produced by alternative splicing e. They are the products of separate A- and B-chain mRNA synthesized from alternative promoters
What amino acid residue of phosphoglucomutase is able to transfer the phosphoryl group to glucose 1-phosphate? A. phosphorylated serine residue B. acetylated lysine residue C. phosphorylated tyrosine residue D. phosphorylated lysine residue E. acetylated serine residue
What is/are product(s) from commensal bacteria that regulate the expression for ler, regulator of genes in EHEC? a. Succinate b. Ethanolamine c. Fucose and sucrose d. None of these answers e. hydrogen   thanks!!!!!!

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Genetics: Analysis and Principles

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