Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 17, Problem 32P
Interpretation Introduction
Interpretation:
The reason for the GTP molecule or another nucleoside triphosphate is actively similar to an ATP molecule in the
Concept introduction:
The citric acid cycle (TCA) is a catabolic process. It is a series of
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Chart is Given for you: Below is a chart of values for actual enzymes.
Enzyme Km (M) kcat (1/s)Chymotrypsin 1.5 × 10^−2 0.14Pepsin 3.0 × 10^−4 0.5Tyrosyl-tRNA synthetase 9.0 × 10^−4 7.6Ribonuclease 7.9 × 10^−3 7.9 × 10^2Carbonic anhydrase 2.6 × 10^−2 4.0 × 10^5Fumarase 5.0 × 10^−6 8.0 × 10^2
Assume the enzyme concentration is equal across all samples (and is equal to 1).
(Answer a and b only)a. Which enzyme will have the highest V0 at very high substrate concentrations? (1 M). Why?
b. Which will have the highest V0 at very low substrate concentrations (5.0 × 10^−12). Why?
Fill in the blanks (write answers only in
correct sequence).
When the activation energy required is less
between the reactants and the products, reaction
is known as-----
i.
ii.
The region of an enzyme where substrate
molecules bind and undergo a chemical
11.
reaction is known as---
11.
To produce amino acids and synthesis of
NADH, cycle used is--
Metabolic cycle that takes place both in
cytoplasm and mitochondria is---
Glucose 1 phosphate is converted to Glucose 6
Phosphate by the action of -
Which vitamin deficiency is linked with the
night blindness? Name it
iv.
V.
vi.
Protein synthesis is energetically expensive. Consider the hydrolysis of ATP
into AMP as equivalent to 2 ATP, and both ATP and GTP as energetically
equivalent. In a cell-free system, how many ATP equivalents are required to
incorporate 32 amino acids into a growing peptide chain?
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Full length resilin that is not in a cell is thought by some to form a tertiary structure of this form (picture attached) The yellow portions represent exon 1 and the blue portions exon 3. These structures assemble into a kind of lattice or network. In full length resilin, stress in the form of mechanical pressure or heating to remove water results in a tighter network that excludes any water internally. How might this behavior of resilin produce its ‘elasticity’? Explain how the looser water containing structure and the tighter water excluding structure may give us a mechanism for the elasticity.arrow_forwardDrag the terms on the left to the appropriate blanks on the right to complete the sentences. Terms can be used once, more than once, or not at all. Submit dCTP GMP AMP GTP dTTP activation inhibition dGTP My Answers Give Up UTP + Gln + ATP → CTP + Glu+ ADP + P₁. Cofactor: dCMP + H₂O →→→→DUMP + NH3. Cofactor: CDP+ [2H] → dCDP+ H₂O. Cofactor: Effect: Effect: Effect: Reset Helparrow_forwardWhat is the smallest number of molecules of ATP and GTP consumed in the synthesis of a protein with 200 residues after mRNA synthesis, starting from amino acids? Assume that the hydrolysis of PP; is equivalent to the hydrolysis of ATP for this calculation. number of ATP molecules: number of GTP molecules: 400 800 Incorrectarrow_forward
- The nucleoside monophosphates are seen in metabolic pathways because their phosphoric anhydride bonds can be hydrolyzed off for energy. True Falsearrow_forwardOverall RNA metabolism and proteins involved are regulated by ubiquitin signaling. Explain how ubiquitination plays role in maintaining certain levels of proteins needed by including the process of protein degradation, ubiquitination, any enzymes, proteasome, any ATP hydrolysis. PLEASE do not provide me with a super long answer. Short and to the point would be greatly appreciated!!!!!arrow_forwardExplain why a protein tyrosine phosphatase would include an SH2 domain in addition to its phosphatase domain.arrow_forward
- "Binding of extracellular ligands to receptor tyrosine kinases (RTKs) activates the intracellular catalytic domain by propagating a conformational change across the lipid bilayer through a single transmembrane a helix" is true or false.arrow_forwardProteases are enzymes that cleave peptide bonds using general acid–base catalysis. General acid–base catalysis relies on a proton donor or acceptor other than water. Proteases rely on proton transfer to create strong nucleophiles from active-site amino acid residues. In the protease chymotrypsin, an active-site serine is a potent nucleophile. A nearby residue, His 57, interacts with serine to increase its reactivity. A schematic of chymotrypsin’s active site illustrates the active site Ser 195 and His 57 R groups. The Asp 102 residue helps position the His 57 residue via hydrogen bonding.arrow_forwardSome hormone-signaling pathways result in the phosphorylation of tyrosine resides in proteins. Draw the structure of a phosphotyrosine side chain.arrow_forward
- The Shine-Dalgarno sequence binds to sequence within the large ribosomal subunit so that ribosomes can properly assemble. The parameter that will definitely differ between an enzyme-catalyzed reaction and the corresponding uncatalyzed reaction is the free energy difference between products and reactants.arrow_forwardBactrim, a sulfa antibiotic kill bacterial cells by competitively inhibiting bacterial folic acid synthesis. Which of the following explain WHY, this anti- metabolite antibiotic causes bacterial chromosome loss? High concentrations of sulfa drugs denature all proteins Low concentrations of this sulfa drug are enough to permanently bind nucleic acids High concentrations of this sulfa drug allow binding to the active site of the enzyme permanently denaturing it by inducing oxygen toxicityarrow_forwarda protease that cleave peptide bonds adjacent to aspartate and glutamate would likely have an s1 pocket that contain positively charged amino acids true or falsearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning