Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 17, Problem 5P
Interpretation Introduction
Interpretation: The enzyme/s which do not produce a molecule of carbon dioxide in catalysis needs to be determined.
Concept Introduction:
The citric acid cycle is a catabolic process. It is also known as the TCA cycle or Krebs cycle. It is a series of
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24. Backward. In what way is the electron transfer in ferridoxin-
NADP reductase similar to that of the pyruvate
dehydrogenase complex?
. In deciding which form of isocitrate dehydrogenase plays the more
important role in the citric acid cycle-the NAD*-dependent or
the NADP*-dependent form-what kinds of information would
help you?
This is the ATP accounting question. You are limited to the carbon in the following molecules:
One xylulose 5-phosphate, One glyceraldehyde 3-phosphate, One sedoheptulose 7-phosphate, 1 Oxaloacetate, and 3 carbon dioxide
A) Disregard regulation completely regarding pathway activity, using only the enzymes of glycolysis, pentose phosphate pathway, and citric acid cycle, what is the maximum ATP one can generate with these molecules?
B) Disregard regulation completely regarding pathway activity, using only the enzymes of glycolysis, Calvin- Benson-Bassham cycle, and citric acid cycle, what is the maximum ATP one can generate with these molecules (in this instance only, you also are given 3 ATP and note that you do NOT need to regenerate substrates for rubisco once you get through this enzyme).
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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- Select the best answer. What pathways generate reduced cofactors (NADH or FADH2) for the Electron Transport Chain to use? 1. Glycolysis 2. Gluconeogenesis 3. Pyruvate Dehydrogenase Complex Reaction 4. Citric Acid Cycle 5. Fatty Acid β-Oxidation Question 18 options: 1, 3, 4 2, 3, 4 1, 3, 4, 5 2, 3, 4, 5 1, 2, 3, 4, 5arrow_forwardI. ATP Calculation A. Given that three molecules of glucose underwent full oxidation, how many of the following is produced in each phase? Show your solutions. Glycolysis NADH FADH₂ ATP A B C Pyruvate Oxidation D E F G H I Kreb's Cyclearrow_forward2B. Calculate the total number of ATP that will be generated from the complete B-oxidation of oncobic acid (CH:(CH,),CH=CH(CH,),COOH; 15:1 cis-A9) in an organism that has all the standard required enzymes for metabolism but which pumps only 2 H" in complex I, 0 H' in complex II, 2 H* in complex III and 4 H' in complex IV. The F,F, ATPase is composed of 3 a/ß subunits and 10 c subunits. Show all of your calculations. HOarrow_forward
- Use your knowledge of fat metabolism. glycolysis, the TCA cycle, and axidative phosphorylation to determine how many molecules of ATP eauvalents are produced when glycerol undergoes biochemical combustion. Assume that each molecule of NADH produces 2.5 ATP and that each molecule of FADH2 produces 1.5 molecules of ATP during oxidative phosphorylation. Note that GTP is an ATp "equivalent." OA 14.5 OB. 17 OC. 19.5 OD. 20.5arrow_forwardI. ATP Calculation A. Given that three molecules of glucose underwent full oxidation, how many of the following is produced in each phase? Show your solutions. Glycolysis NADH FADH₂ ATP NADH FADH2 A B C ATP (Substrate Level) SUM TOTAL J K D E [1] F Pyruvate Oxidation F If this happens in the liver, how many ATPs will be synthesized if all NADH and FADH₂ entered ETC.. Total number L M N G H I O Kreb's Cycle ATP Producedarrow_forward. Identify the Krebs cycle enzyme which acts on a five-carbon substrate, produces a four-carbon product substituent (attached to coenzyme A), and generates one molecule of NADH. a-ketoglutarate dehydrogenase pyruvate dehydrogenase citrate synthase malate dehydrogenase succinate dehydrogenase Which of the following enzymes consumes one molecule of NADH, during anaerobic fermentation in yeast, as it converts a two-carbon substrate molecule into a two-carbon product molecule? succinate dehydrogenase pyruvate decarboxylase C. isocitrate dehydrogenase lactate dehydrogenase alcohol dehydrogenasearrow_forward
- Fill in the blanks below (input numbers only!) about the metabolism of hexanoic acid, a fatty acid that is one of the components of vanilla, and whose formula is CH3(CH2)4COOH: First, the fatty acid is activated by attaching CoA, which costs ATP molecules. The fatty acid is then broken down through a beta-oxidation spiral, to make acetyl CoA molecules. This will require "turns" of the beta-oxidation process. Since each turn of the cycle yields ATP molecules, and each acetyl COA will yield ATP molecules by going through the rest of its metabolism, the net ATP molecules produced from one molecule of this fatty acid will bearrow_forwardComplete the interrelated pathways by choosing the necessary metabolite, enzyme, coenzyme, reaction, and metabolic pathway. UDP- glucose 1- phosphate glucose-6- phosphate ribulose S-phosphate glucose 4. reduced coenzyme glycogen Ala 1. pathway 2. metabolite Pyruvate Glu 3. enzyme 7. reaction NH. 5. pathway ATP + HCO. acetyl CoA +3cetcacetate oxaloacetate 6 final oxidized product fumarate auraruuo & pathway citrullinearrow_forward5 Enzyme involved in removing carboxyl groups. Reduces molecules by removing H (and electrons) from NADH. Catalyzes the interconversion of 3- Phosphoglycerate to 2-Phosphoglycerate by relocating the phosphate functional group. Transfers a phosphate group from phosphoenolpyruvate to ADP to give pyruvate and ATP. group Plays a role in removing phosphate Answers Select match Dehydrogenase Mutase Phosphatase Decarboxylase Kinase Carboxykinasearrow_forward
- Which statement does NOT describe a general function of the pentose phosphate pathway? Group of answer choices The pentose phosphate pathway is used to produce NADPH for reductive biosynthesis in adipocytes. The pentose phosphate pathway allows for the entry of dietary pentose intermediates into the glycolytic pathway. The pentose phosphate pathway produces reduced molecules whose electrons may be shuttled to the mitochondria for oxidative phosphorylation. The pentose phosphate pathway allows for the conversion of hexoses into pentoses that may be used as precursors in the synthesis of nucleosides.arrow_forward7. Flow of carbon atoms. What is the fate of the radioac- tive label when each of the following compounds is added to a cell extract containing the enzymes and cofac- tors of the glycolytic pathway, the citric acid cycle, and the pyruvate dehydrogenase complex? (The ¹4C label is printed in red.) (a) (c) H3C H3C O C. O C. COO COO- (b) (d) H3C H₂C O C. O C. (e) Glucose 6-phosphate labeled at C-1. COO™ S-COAarrow_forward36. What is the CORRECT order of cellular respiration events? Group of answer choices glycolysis—pyruvate oxidation—Krebs cycle—oxidative phosphorylation glycolysis—Krebs cycle—pyruvate oxidation--oxidative phosphorylation Krebs cycle—oxidative phosphorylation--glycolysis—pyruvate oxidation Krebs cycle—glycolysis--oxidative phosphorylation—pyruvate oxidationarrow_forward
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