Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 17, Problem 4P
Interpretation Introduction
Interpretation: The complex similar to the pyruvate dehydrogenase complex needs to be determined.
Concept Introduction:
The citric acid cycle is a catabolic process. It is also known as the TCA cycle or Krebs cycle. It is a series of
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Long explanations are not needed. Direct answers would suffice.
a. High concentration of glucose 6-phosphate is inhibitory to the enzyme hexokinase.
I. True
II. False
b. Which compound is formed when NAH reduces pyruvate (anaerobic condition)?
I. lactate
II. alpha-ketoglutarate
III. glucose
IV. oxaloacetate
Butch Cassidy and the Sundance Kid. Glutamate dehydrogenase
requires which of the following cofactors:
a. NAD+/NADP+NAD*/NADP+
b. Pyridoxal phosphate
c. Thiamine pyrophosphate
d. Biopterin
Long explanations are not needed. Direct answers would suffice.
a. In the TCA cycle, succinate dehydrogenase channels electrons directly into the electron transfer chain.
I. True
II. False
b. Glucagon is a hormone that activates glycogenolysis.
I. True
II. False
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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- Long explanations are not needed. Direct answers would suffice. a. Ribose-5-phosphate is produced by oxidative decarboxylation of 6-phosphogluconate catalyzed by the enzyme glucose-6-phosphate dehydrogenase. I. True II. False b. The pentose phosphate pathway occurs in the mitochondrion of tissues actively engaged in synthesis of fatty acids. I. True II. Falsearrow_forwardLong explanations are not needed. Direct answers would suffice. a. Transketolases catalyze two-carbon fragment transfer from sedoheptulose-7-phosphate to xylose-5-phosphate. i. True ii. False b. High concentration of NADPH increases the rate of the pentose phosphate pathway by stimulating glucose-6-phosphate dehydrogenase. i. True ii. Falsearrow_forwardLong explanations are not needed. Direct answers would suffice. ***kind of in hurry so having the answer asap would greatly be appreciated, thank you :)) a. The first step in the pay-off phase of glycolysis is the oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. i. True ii. False b. Phosphofructokinase-1, the major flux-controlling enzyme of glycolysis is inhibited by _______. i. AMP ii. ATP iii. ADP iv. phosphoenol pyruvatearrow_forward
- Select the best answer. What pathways generate reduced cofactors (NADH or FADH2) for the Electron Transport Chain to use? 1. Glycolysis 2. Gluconeogenesis 3. Pyruvate Dehydrogenase Complex Reaction 4. Citric Acid Cycle 5. Fatty Acid β-Oxidation Question 18 options: 1, 3, 4 2, 3, 4 1, 3, 4, 5 2, 3, 4, 5 1, 2, 3, 4, 5arrow_forwardClosely related. Pyruvate dehydrogenase complex and a-ketoglutarate a-ketoglutarate dehydrogenase complex are huge enzymes consisting of three discrete enzymatic activities. Which amino acids require a related enzyme complex, and what is the name of the enzyme?arrow_forwardLong explanations are NOT NEEDED. I pretty much have an idea already about this lesson, I would just like to see if my answers are correct, if it's wrong then kindly correct and just add a short explanation. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. a. Number of pyruvate molecules after glycolysis is 4.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.c. Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1.d. Number of NADH and FADH2 produced from Krebs cycle is 12 and 4 respectively.e. Net ATP produced (complete oxidation via Malate aspartate shuttle) is 64.arrow_forward
- true or false 1. Phosphoenolpyruvate carboxykinase is the enzyme involved in the carbon dioxide fixation in the mesophyll cells of C4 plants 2. The C4 pathway utilizes less ATP than C3 pathway thus enabling C4 plants to adapt to tropical temperatures. 3. Photorespiration occurs when [O2]/[CO2] is high. 4. The carboxylase activity of RuBisCO catalyzes the fixation of carbon dioxide. 5. In cyclic photophosphorylation, only ATP is produced. 6. Chlorophyll has iron as the metal center of the porphyrin ring.arrow_forwardSelect the BEST answer. Increasing the concentration of Fructose-2,6 bisphosphate would Inhibit Phosphofructokinase 2 Increase the concentration of Fructose-1,6 bisphosphate (phosphofructose isomerase) O increase the synthesis of glycogen Increase the carboxylation of Ac-CoA to make more malonyl-CoA increase the concentration of Pyruvatearrow_forwardLong explanations are NOT NEEDED. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. a. Number of pyruvate molecules after glycolysis.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation).c. Number of NADH produced using the pyruvate dehydrogenase complex reaction.d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward
- G. ENZYME CLASSIFICATION. Identify the main class of enzymes used to catalyzed the following reactions: 1. Lactate dehydrogenase: NADH+H NAD HC-OH CH3 CH Pynnte Lactate 2. Methylmalonyl-CoA mutase: CH CH SCOA CH,CH, SCOA coenzyme B12 COO COO methylmalonyl-CoA succinyl-CoA 3. Enolase: 0. H–Ċ–0–P–0- C-0–P-0- + H,0 HO–CH, CH 6 Phosphoenolpyruvate 2-Phosphoglycerate 4. Chymotrypsin: -0–CH,CH3 + H2O - RCOOH + HOCH,CH3 5. Pyruvate carboxylase: coo • co, • ATP + H,0 H-C-H . ADP + P, + 2H čoo CH, Pyruvate Oxaleacetatearrow_forward. Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.arrow_forwardfill in the blanks The pyruvate dehydrogenase complex is primarily regulated at the ( ) which has a ( ) prosthetic group.arrow_forward
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