Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 17, Problem 4P
Interpretation Introduction
Interpretation: The complex similar to the pyruvate dehydrogenase complex needs to be determined.
Concept Introduction:
The citric acid cycle is a catabolic process. It is also known as the TCA cycle or Krebs cycle. It is a series of
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In this scenario, a patient has beriberi. Beriberi patients can be treated through a thiamine-enriched diet. The patient was put on a thiamine-enriched diet but not all of their symptoms were alleviated. Through genetic testing, it was found that there was also a small defect in pyruvate dehydrogenase phosphatase that decreases its normal activity.
1. Explain why this genetic defect can cause beriberi symptoms (i.e. high pyruvate levels after a high-carb meal).
2. Why did thiamine supplementation not alleviate the symptoms for this patient?
Select the best answer. What pathways generate reduced cofactors (NADH or FADH2) for the Electron Transport Chain to use?
1. Glycolysis
2. Gluconeogenesis
3. Pyruvate Dehydrogenase Complex Reaction
4. Citric Acid Cycle
5. Fatty Acid β-Oxidation
Question 18 options:
1, 3, 4
2, 3, 4
1, 3, 4, 5
2, 3, 4, 5
1, 2, 3, 4, 5
Please help me with question.
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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- Need help, please. Given that the enzyme pyruvate carboxylase converts Pyruvate into Oxaloacetate and this is an anapleurotic reaction. In the liver, what is most of the OAA converted into under these conditions? Please explain. 1. When blood glucose levels are low and the energy charge in the cell is high. 2. When mitochondrial acetyl-CoA levels are high and the energy charge is low.arrow_forwardClosely related. Pyruvate dehydrogenase complex and a-ketoglutarate a-ketoglutarate dehydrogenase complex are huge enzymes consisting of three discrete enzymatic activities. Which amino acids require a related enzyme complex, and what is the name of the enzyme?arrow_forwardPls answer.arrow_forward
- choose the correct answer.arrow_forwardGive detailed Solution with explanation needed..don't give Handwritten answerarrow_forwardG. ENZYME CLASSIFICATION. Identify the main class of enzymes used to catalyzed the following reactions: 1. Lactate dehydrogenase: NADH+H NAD HC-OH CH3 CH Pynnte Lactate 2. Methylmalonyl-CoA mutase: CH CH SCOA CH,CH, SCOA coenzyme B12 COO COO methylmalonyl-CoA succinyl-CoA 3. Enolase: 0. H–Ċ–0–P–0- C-0–P-0- + H,0 HO–CH, CH 6 Phosphoenolpyruvate 2-Phosphoglycerate 4. Chymotrypsin: -0–CH,CH3 + H2O - RCOOH + HOCH,CH3 5. Pyruvate carboxylase: coo • co, • ATP + H,0 H-C-H . ADP + P, + 2H čoo CH, Pyruvate Oxaleacetatearrow_forward
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