Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 17, Problem 36P
Interpretation Introduction
Interpretation:
The effect of the breakdown of fatty acid on the activity of pyruvate dehydrogenase complex and glycolysis.
Concept introduction:
Glycolysis is a catabolic process. In this process, one glucose molecule is converted into two molecules of pyruvate. The energy released during this process is useful in the formation of high-energy adenosine triphosphate (ATP) molecules and reduced nicotinamide adenine (NADH) molecules.
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Butch Cassidy and the Sundance Kid. Glutamate dehydrogenase
requires which of the following cofactors:
a. NAD+/NADP+NAD*/NADP+
b. Pyridoxal phosphate
c. Thiamine pyrophosphate
d. Biopterin
Long explanations are NOT NEEDED. I pretty much have an idea already about this lesson, I would just like to see if my answers are correct, if it's wrong then kindly correct and just add a short explanation.
ATP accounting.
Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation.
a. Number of pyruvate molecules after glycolysis is 4.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.c. Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1.d. Number of NADH and FADH2 produced from Krebs cycle is 12 and 4 respectively.e. Net ATP produced (complete oxidation via Malate aspartate shuttle) is 64.
Long explanations are not needed.
True or Falsea. One NADH is produced for every pyruvate molecule undergoing oxidation using the enzyme pyruvate dehydrogenase complex
b. Erythrose-4-phosphate can be synthesized using the pentose phosphate pathway.
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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- . Describe the reaction steps of the citric acid cycle with a focus on their control. In addition discuss the energy provided to a living cell from the metabolism of one acetyl-CoA entering the citric acid cyclearrow_forwardClosely related. Pyruvate dehydrogenase complex and a-ketoglutarate a-ketoglutarate dehydrogenase complex are huge enzymes consisting of three discrete enzymatic activities. Which amino acids require a related enzyme complex, and what is the name of the enzyme?arrow_forwardUse your knowledge of fat metabolism. glycolysis, the TCA cycle, and axidative phosphorylation to determine how many molecules of ATP eauvalents are produced when glycerol undergoes biochemical combustion. Assume that each molecule of NADH produces 2.5 ATP and that each molecule of FADH2 produces 1.5 molecules of ATP during oxidative phosphorylation. Note that GTP is an ATp "equivalent." OA 14.5 OB. 17 OC. 19.5 OD. 20.5arrow_forward
- G. ENZYME CLASSIFICATION. Identify the main class of enzymes used to catalyzed the following reactions: 1. Lactate dehydrogenase: NADH+H NAD HC-OH CH3 CH Pynnte Lactate 2. Methylmalonyl-CoA mutase: CH CH SCOA CH,CH, SCOA coenzyme B12 COO COO methylmalonyl-CoA succinyl-CoA 3. Enolase: 0. H–Ċ–0–P–0- C-0–P-0- + H,0 HO–CH, CH 6 Phosphoenolpyruvate 2-Phosphoglycerate 4. Chymotrypsin: -0–CH,CH3 + H2O - RCOOH + HOCH,CH3 5. Pyruvate carboxylase: coo • co, • ATP + H,0 H-C-H . ADP + P, + 2H čoo CH, Pyruvate Oxaleacetatearrow_forwardTrue or false? Under anaerobic conditions, the pyruvate dehydrogenase complex is responsible for the irreversible conversion of pyruvate to acetyl CoA.arrow_forwardLong explanations are NOT NEEDED. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward
- . Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.arrow_forwardFollowing glycolysis. Most of the energy from the original glucose is in the form of: O A. high-energy electrons that are associated with electron carriers. О В. АТР О С. Н20 D. CO2 O E. pyruvic or lactic acid A Moving to another question will save this response.arrow_forwardLong explanations are NOT NEEDED. Answer only d and e. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. -Number of pyruvate molecules after glycolysis is 4.-Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.-Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1. Now find:d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward
- . In deciding which form of isocitrate dehydrogenase plays the more important role in the citric acid cycle-the NAD*-dependent or the NADP*-dependent form-what kinds of information would help you?arrow_forwardSelect the BEST answer. Increasing the concentration of Fructose-2,6 bisphosphate would Inhibit Phosphofructokinase 2 Increase the concentration of Fructose-1,6 bisphosphate (phosphofructose isomerase) O increase the synthesis of glycogen Increase the carboxylation of Ac-CoA to make more malonyl-CoA increase the concentration of Pyruvatearrow_forwardSelect the best answer. What pathways generate reduced cofactors (NADH or FADH2) for the Electron Transport Chain to use? 1. Glycolysis 2. Gluconeogenesis 3. Pyruvate Dehydrogenase Complex Reaction 4. Citric Acid Cycle 5. Fatty Acid β-Oxidation Question 18 options: 1, 3, 4 2, 3, 4 1, 3, 4, 5 2, 3, 4, 5 1, 2, 3, 4, 5arrow_forward
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