Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 17, Problem 29P
Interpretation Introduction
Interpretation:
The reason for acetyl CoA is a specifically suitable activator for pyruvate carboxylase.
Concept introduction:
The citric acid cycle (TCA) is a catabolic process. It is a series of
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BIOCHEMISTRY. Could glycerol be used to regenerate the OAA for maintenance of TCA cycle activity? Yes or No? Explain.
G. ENZYME CLASSIFICATION.
Identify the main class of enzymes used to catalyzed the following reactions:
1. Lactate dehydrogenase:
NADH+H
NAD
HC-OH
CH3
CH
Pynnte
Lactate
2. Methylmalonyl-CoA mutase:
CH CH
SCOA
CH,CH,
SCOA
coenzyme B12
COO
COO
methylmalonyl-CoA
succinyl-CoA
3. Enolase:
0.
H–Ċ–0–P–0-
C-0–P-0- + H,0
HO–CH,
CH 6
Phosphoenolpyruvate
2-Phosphoglycerate
4. Chymotrypsin:
-0–CH,CH3 + H2O
- RCOOH + HOCH,CH3
5. Pyruvate carboxylase:
coo
• co, • ATP + H,0
H-C-H . ADP + P, + 2H
čoo
CH,
Pyruvate
Oxaleacetate
. Pyruvate can be processed under anaerobic conditions to ethanol (in yeast) or to lactate (in
mammals), as shown.
Explain the primary purpose of these reactions.
Describe the major biochemical features of each reaction
Chapter 17 Solutions
Biochemistry
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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- Fill in the blanks. Acetaminophen toxicity can occur at high doses in the liver. because ___________ (what type of molecules?) can become saturated and other routes of metabolism take over.Please explain to me what the correct molecule(?) is and why it is correct. I understand that the glucuronidation and sulfation conjugation pathways become saturated, but am not understanding what molecule(s) it is/are that is/are becoming saturated leading to the other routes of metabolism and acetaminophen toxicity.arrow_forwardX INCORRECT; see section 13.1 Enzymes occasionally display weak "“side" activities. Draw the structure of the product (other than ADP) of the reaction that results when pyruvate kinase, operating in reverse, uses lactate as a substrate. For your structure: 1. Do not include primary or secondary hydrogens. CH2 HO OH Edit Drawingarrow_forward27. Working at cross-purposes . Write a balanced equation showing the effect of simultaneous activation of glycogen phosphorylase and glycogen synthase. Include the reactions catalyzed by phosphoglucomutase and UDP-glucose pyrophosphorylase.arrow_forward
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- Function of citric acid? Give me handwritten answer with explaination?arrow_forwardConsidering the complete oxidation of an 18-C fatty acid. Give the answer for the following question.a. How many rounds of beta-oxidation is needed?b. How many NADH molecules are produced in beta-oxidation only?c. How many FADH2 molecules are produced in beta-oxidation only?d. How many Acetyl Co-A are produced?arrow_forwardLong explanations are not needed. True or Falsea. One NADH is produced for every pyruvate molecule undergoing oxidation using the enzyme pyruvate dehydrogenase complex b. Erythrose-4-phosphate can be synthesized using the pentose phosphate pathway.arrow_forward
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