To identify which of the given reaction is not feasible. Concept introduction: The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

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Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

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Students have asked these similar questions

Why is it not advisable to use aqueous hydrochloric acid in a Grignard reaction of a ketone? A) The Grignard reagent will react with the acid and cannot react with the ketone. B) The ketone will be protonated and will become unreactive. C) The ketone will form an unreactive enol. D) The Grignard reagent won't dissolve in aqueous solutions

Which of the following molecules would react quickest via an aromatic substitution process? electrophillic a. b. c. O d.

Explain why two substitution products are formed in the following reaction.

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

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Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

Expert Solution & Answer

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Answer 5

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

Answer 6

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

Answer 7

Chapter 16, Problem 71P

(a)

Interpretation Introduction

Interpretation:

To identify which of the given reaction is not feasible.

Concept introduction:

The carboxylic acid and its derivatives undergo nucleophilic acyl substitution reaction. The incoming group is called as a nucleophile and the substituent that departs from a molecule is known as leaving the group. If the attacking group is a good base or poor leaving group as compared to the substituent that is already present in the tetrahedral intermediate than attacking group will replace the existing substituent or good leaving group and reaction will be feasible.

Answer 8

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

Answer 9

(b)

Interpretation Introduction

Interpretation:

To identify the reactions which are not feasible in the above part of the question can be made feasible by adding an acid catalyst.

Concept introduction:

The aminolysis reaction and the hydrolysis of ester can be made feasible by the addition of acid catalyst in the reaction mixture.

The acid catalyst first protonates the carbonyl oxygen thus increses the electrophillitcity of the carbonyl carbon and also protonates the nitogen atom making it good leaving group. Thus, the rate of reaction increases.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 16.1 - The aromas of many flowers and fruits are due to...Ch. 16.1 - Prob. 2P Ch. 16.1 - Name the following:Ch. 16.1 - Prob. 4P Ch. 16.2 - Prob. 5P Ch. 16.2 - Which is longer, the carbon-oxygen single bond in...Ch. 16.2 - There are three carbon-oxygen bonds in methyl...Ch. 16.2 - Prob. 8P Ch. 16.4 - Prob. 9P Ch. 16.4 - Prob. 10P

Solution Summary: The author explains that the nucleophilic acyl substitution reaction of carboxylic acid and its derivatives is not feasible.

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