Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 16, Problem 19PDQ
Summary Introduction

To review:

The role of “heterozygosity loss” in the cancer development.

Introduction:

Heterozygosity is the condition of having two contrasting alleles at a gene locus in a diploid organism. Out of these two alleles, one is dominant while the other one is recessive. According to the population genetics, the fitness of a heterozygous individual is high as compared to a homozygous individual. Loss of heterozygosity leads to genetic variation and development of various genetic disorders and cancer.

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