Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 16, Problem 13PDQ
Summary Introduction
To review:
(A) Difference between oncogenes and proto-oncogenes.
(B) Ways to convert proto-oncogenes to oncogenes.
Introduction:
In humans, a normal cell possesses proto-oncogene that regulates proper cell cycle and division. If these normal genes are introduced to a carcinogen then it goes under mutation, which converts the proto-oncogenes into oncogene and results in cancer.
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Students have asked these similar questions
Describe the general functions of oncogenes.
What is a proto-oncogene? What are the typical functions of proteinsencoded by proto-oncogenes? At the level of protein function,what are the general ways that proto-oncogenes can beconverted to oncogenes?
Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.
Select the two mechanisms.
Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two mechanisms.
1) alterations in chromatin structure
2) a gain-of-function alteration
3)modification of proto-oncogenes products
4)mutations that result in an abnormal protein product
5)mutations within gene-regulatory regions
Chapter 16 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 16 -
2. Review the Chapter Concepts list on page 307....Ch. 16 - What is the relationship between signal...Ch. 16 - Where are the major regulatory points in the cell...Ch. 16 -
5. Describe kinases and cyclins. How do they...Ch. 16 - (a) How does pRB function to keep cells at the G1...Ch. 16 - What is the difference between saying that cancer...
Ch. 16 -
8. What is apoptosis, and under what...Ch. 16 - Define tumor-suppressor genes. Why is a mutation...Ch. 16 - A genetic variant of the retinoblastoma protein,...Ch. 16 -
11. Part of the Ras protein is associated with...Ch. 16 - If a cell suffers damage to its DNA while in S...Ch. 16 - Prob. 13PDQCh. 16 - Prob. 14PDQCh. 16 - Prob. 15PDQCh. 16 - Prob. 16PDQCh. 16 - Prob. 17PDQCh. 16 - How do normal cells protect themselves from...Ch. 16 - Prob. 19PDQCh. 16 - Explain how environmental agents such as chemicals...Ch. 16 - Radiotherapy (treatment with ionizing radiation)...Ch. 16 - Genetic tests that detect mutations in the BRCA1...Ch. 16 - Prob. 23PDQCh. 16 - Prob. 24PDQCh. 16 - Prob. 25PDQCh. 16 - Prob. 26PDQCh. 16 - Prob. 27PDQCh. 16 - Prob. 28PDQ
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- What are oncogenes?arrow_forwardSuppose a gain-of-function mutation happens in an oncogene. Which of the following changes is likely to result? O a) tumor-promoting inflammation O b) evading growth suppressors Oc) sustaining proliferative signalling O d) resisting cell deatharrow_forwardHow can oncogenes lead to cancer?arrow_forward
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