Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 12.4, Problem 1CC
Summary Introduction
To explain: The effect on transcription and translation if the start codon from a protein-encoding gene is eliminated by mutation.
Introduction: The genetic expression of gene follows directionality of the flow of the information according to the mechanism of the central dogma. The transcription process includes the flow of the genetic information from a segment of the DNA to make complementary mRNA fragment. The mRNA molecules are then undergoes capping and addition of poly A tail to be able to move from nucleus to the site of translation. The translation occurs at ribosomes and converts the information stored in mRNA codons to be finally expressed as chain of amino acid joined by the peptide bond know as protein.
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If a mutation eliminated the start codon from a gene, howwould the mutation affect transcription, and how would it affect translation?
If the base sequence of a segment of a molecule of DNA is changed, will the base sequence of the mRNA made during transcription be changed?
Why will a mistake in the RNA code alone not become a mutation?
Chapter 12 Solutions
Biology
Ch. 12.1 - What disease would result if a person inherited...Ch. 12.1 - Prob. 2CCCh. 12.1 - What is the direction of flow of genetic...Ch. 12.2 - Core Skill: Connections Look back at the role of...Ch. 12.3 - Prob. 1CCCh. 12.4 - Prob. 1CCCh. 12.4 - Prob. 1EQCh. 12.4 - Prob. 2EQCh. 12.4 - Prob. 3EQCh. 12.5 - Core Skill: Connections Look back at Figure 6.3,...
Ch. 12.5 - Prob. 2CSCh. 12.6 - Prob. 1CCCh. 12 - Which of the following best represents the central...Ch. 12 - A mutation prevents a gene from being transcribed...Ch. 12 - Prob. 3TYCh. 12 - Prob. 4TYCh. 12 - If a eukaryotic mRNA failed to have a cap attached...Ch. 12 - Prob. 6TYCh. 12 - Prob. 7TYCh. 12 - During the initiation of translation, the first...Ch. 12 - Prob. 9TYCh. 12 - Prob. 10TYCh. 12 - Prob. 1CQCh. 12 - Prob. 2CQCh. 12 - Prob. 3CQCh. 12 - Prob. 1COQCh. 12 - Prob. 2COQ
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- A mutation within a gene sequence changes the start codon to a stop codon. How will this mutation affect the transcription of this gene?arrow_forwardHow is transcription different from translation with respect to location, template and end product?arrow_forwardWhat is the role of Mediator in transcription?arrow_forward
- What percent of the transcription in a human cell makes protein-coding RNA, and what percent of transcription makes non-coding RNA?arrow_forwardHow is the mRNA strand altered during mRNA processing (the intermediate step between transcription and translation)? How are these modifications helpful?arrow_forwardWhat happens when one base pair of DNA is lost from the coding region of a gene because of mutation? First explain how this would affect the mRNA sequence, and second, explain how this would alter the amino acid of the protein that is encoded.arrow_forward
- A substitution mutation that results in the formation of a stop codon and premature termination of the protein is called?arrow_forwardIf a mutation changed the start codon into a stop codon, would this mutation affect the length of the RNA? Explain.arrow_forwardWhat is the role of DNA in transcription?arrow_forward
- What is the mechanism by which a riboswitch regulates translation?arrow_forwardWhat happens in initiation, elongation, and termination during translation?arrow_forwardSome mutations that do not alter the identity of the encoded amino acid lead to diminished production of the protein. How does the mutation affect translation?arrow_forward
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