Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Textbook Question
Chapter 12, Problem 5TY
If a eukaryotic mRNA failed to have a cap attached to its 5′ end, what would the negative consequence(s) be?
- a. The mRNA would not properly exit the nucleus.
- b. The mRNA would not properly bind to a ribosome.
- c. The mRNA would not receive a poly A tail.
- d. The mRNA would not use the correct start codon.
- e. both a and b
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Students have asked these similar questions
The addition of the poly-A tail adds more than 200 units of adenine to the strand of mRNA, yet no protein has a continuous line of more than 200 phenylalanines in its structure. Why is this so?
A. RNA splicing occurs and removes the noncoding sequences.
B. The poly-A tail and 5' GTP cap do not translate into proteins.
C. The adenines are reabsorbed by the cell and help to form other forms of RNA.
D. The tRNA does not recognize the poly-A tail.
Why might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA?
a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product.
b. If the mutation occurs in the exon, it will not affect the gene product.
c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may
affected.
O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc
affect the gene product.
O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product.
OLIE STIC N 1A
A geneticist induces a mutation in eukaryote cells. The mutation results in an inability to form the poly(A) tail during processing of pre-mRNA. What does this mean for the mature mRNA and what will be the effect on these cells?
Possible Answers:
A. The mRNA will be spliced, but will not have a 5' cap.
B. The mRNA will likely be degraded.
C. The mRNA will not be cleaved.
D. The mRNA will have too many Gs and Cs.
Chapter 12 Solutions
Biology
Ch. 12.1 - What disease would result if a person inherited...Ch. 12.1 - Prob. 2CCCh. 12.1 - What is the direction of flow of genetic...Ch. 12.2 - Core Skill: Connections Look back at the role of...Ch. 12.3 - Prob. 1CCCh. 12.4 - Prob. 1CCCh. 12.4 - Prob. 1EQCh. 12.4 - Prob. 2EQCh. 12.4 - Prob. 3EQCh. 12.5 - Core Skill: Connections Look back at Figure 6.3,...
Ch. 12.5 - Prob. 2CSCh. 12.6 - Prob. 1CCCh. 12 - Which of the following best represents the central...Ch. 12 - A mutation prevents a gene from being transcribed...Ch. 12 - Prob. 3TYCh. 12 - Prob. 4TYCh. 12 - If a eukaryotic mRNA failed to have a cap attached...Ch. 12 - Prob. 6TYCh. 12 - Prob. 7TYCh. 12 - During the initiation of translation, the first...Ch. 12 - Prob. 9TYCh. 12 - Prob. 10TYCh. 12 - Prob. 1CQCh. 12 - Prob. 2CQCh. 12 - Prob. 3CQCh. 12 - Prob. 1COQCh. 12 - Prob. 2COQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is one function of the 5' cap in eukaryotic mRNA? Select one: a. It is involved in translation termination. b. It is an intron splicing signal. c. It is the initial attachment site for ribosomes. d. It is involved in polyadenylation of the 5' end of the mRNAarrow_forwardA scientist mutates eIF-2 to eliminate its GTP hydrolysis capability. How would this mutated form of eIF-2 alter translation? a. Initiation factors would not be able to bind to mRNA. b. The large ribosomal subunit would not be able to interact with mRNA transcripts. c. tRNAi-Met would not scan mRNA transcripts for the start codon. d. eIF-2 would not be able to interact with the small ribosomal subunit.arrow_forwardWhich of the following statements is INCORRECT? a. In simultaneous transcription of mRNA, many messenger RNA may be transcribed from different DNA strand happening all at once. b. All of the following statements are incorrect c. A poly A - tail is added at the end of the 3’ base. d. In eukaryotic cells, messenger RNA must exit the nucleus and enter the cytoplasmarrow_forward
- The AUC and AUA codons in mRNA both specify isoleucine. What feature of the genetic code explains this? a. complementarity b. nonsense codons c. universality d. degeneracyarrow_forwardEukaryotic mRNA is capped at the 5' end by: a. adding a poly A sequence to the 5' end. b. ligating a 7-methylguanylate via a 3’ linkage. c. methylating the base pairs near the 5’ end. d. forming a lariat structure via transesterification.arrow_forwardImagine that mutations occurred in one of the inverted repeat sequences within the rho-independent terminator sequence of a bacterium. What would likely be the consequence of this mutation? Select one: a. Transcription may not be initiated at all. b. Transcription may end prematurely. c. Transcription may be delayed. d. The rho protein won't be able to bind and transcription may not be terminate. e. Transcription may not be terminated and result in much longer RNA.arrow_forward
- Once a peptide bond has been formed between the amino acid attached to the TRNA in the P site and the amino acid associated with the TRNA in the A site, what process occurs next? a. translocation of the ribosome along the mRNA b. binding of a new tRNA in the E site C. scanning for the start codon d. release of the peptide from the TRNAarrow_forwardWhich of the following statements about RNA processing in eukaryotes is INCORRECT? A. The excision of introns from pre-mRNA is the only modification required to produce a mature mRNA. B. A protein/RNA complex is used to remove introns from the pre-mRNA. C. A poly A tail is added on to the 3′ end of the mRNA. D. A 7-methylguanosine cap is added on to the 5′end of the mRNA. E. Modification occurs in the nucleus.arrow_forwardA particular tRNA is mutated so that the amino acid attachment cannot bind with the aminoacyl-tRNA synthase. What happens when an mRNA transcript contains the codon for this tRNA? A. The tRNA will not bind to this codon. B. Translation stops and the protein is released. C The wrong tRNA is added to the protein chain. D. Translation stops and the protein remains bound to the ribosome.arrow_forward
- If you imagine a messenger RNA molecule in the cytoplasm of a cell, which of the following will likely affect how much protein is made by translation of this message? A. The presence of appropriate snRNPs. B. The length of the polyA tail. C. The strength of hydrogen bonds holding the mRNA to ribosomal RNA. D. The ability of the mRNA to pair with itself to form a helix-turn-helix structure.arrow_forwardWhich of the following is true about the three major classes of RNAs in the cell: mRNAs, tRNAs, and rRNAs? A. mRNAs encode polypeptide chains. B. tRNAs are structural components of the ribosome. C. rRNAs are adapter molecules that translate the information on an mRNA into a polypeptide sequence. D. mRNAs can also encode tRNAs and rRNAs.arrow_forwardWhat would be the direct consequence to a cell of loss-of-function of Elongation Factor-Tu (EF-Tu)? You may select multiple answers. a. tRNAs would fail to exit the E site after giving up their amino acid. b. The error rate of translation would increase. c. The ribosome would frequently fail to identify the correct start codon and initiation of translation would become less efficient. d. There would be no pause between the entry of a tRNA into the A site and peptidyl transfer.arrow_forward
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