Human Physiology: An Integrated Approach (8th Edition)
Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 12.3, Problem 25CC
Summary Introduction

To determine: The structure of sarcomere which is similar to dense bodies that anchor actin fibers of smooth muscles.

Introduction: A sarcomere is a pattern formed in striated muscle tissue due to the arrangement of the thick and thin filaments present in it. Smooth muscles do not have sarcomere; they have similar contractile proteins which interact through cross-bridges.

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As mentioned in class, one additional major use of ATP in skeletal muscle (besides powering the myosin heads) is the recycling of calcium ions back into the sarcoplasmic reticulum after depolarization. The resting concentration of Ca++ in the muscle cell cytoplasm is about 50-100 nM, and the spike concentration after depolarization is about 10-20 μΜ. a) Consider a single sarcomere. What is the number of free calcium ions within the sarcomere at rest? What is the number of free calcium ions after depolarization? b) The major ion pump responsible for calcium ion recycling is SERCA (sarco/endoplasmic reticulum calcium ATPase). SERCA uses one molecule of ATP to pump two calcium ions, and the resting level can be restored in about 10-20 ms. How many molecules of ATP are used in a single sarcomere for pumping calcium in a single "twitch"? c) Assume that a single "twitch" is sufficient to drive one sarcomere from its fully extended length (about 2.5 µm) to its fully contracted length (about 1…

Chapter 12 Solutions

Human Physiology: An Integrated Approach (8th Edition)

Ch. 12.1 - Prob. 11CCCh. 12.1 - Prob. 12CCCh. 12.1 - Prob. 13CCCh. 12.1 - According to the convention for naming enzymes,...Ch. 12.1 - Prob. 15CCCh. 12.1 - Prob. 16CCCh. 12.1 - Summation in muscle fibers means that the...Ch. 12.1 - Prob. 18CCCh. 12.1 - Which type of runner would you expect to have more...Ch. 12.1 - What is the response of a muscle fiber to an...Ch. 12.1 - Prob. 21CCCh. 12.2 - One study found that many world-class athletes...Ch. 12.3 - What is the response of a muscle fiber to an...Ch. 12.3 - Prob. 24CCCh. 12.3 - Prob. 25CCCh. 12.3 - Prob. 26CCCh. 12.3 - Prob. 27CCCh. 12.3 - Prob. 28CCCh. 12.3 - What happens to contraction if a smooth muscle is...Ch. 12.3 - Prob. 30CCCh. 12.3 - Prob. 31CCCh. 12.3 - Prob. 32CCCh. 12.3 - How can a neuron alter the amount of...Ch. 12.3 - Prob. 34CCCh. 12.3 - Prob. 35CCCh. 12 - The three types of muscle tissue found in the...Ch. 12 - Which two muscle types are striated?Ch. 12 - Which type of muscle tissue is controlled only by...Ch. 12 - Arrange the following skeletal muscle components...Ch. 12 - The modified endoplasmic reticulum of skeletal...Ch. 12 - Prob. 6RQCh. 12 - Prob. 7RQCh. 12 - List six proteins that make up the myofibrils....Ch. 12 - List the letters used to label the elements of a...Ch. 12 - Briefly explain the functions of titin and...Ch. 12 - During contraction, the __________ band remains a...Ch. 12 - Explain the sliding filament theory of...Ch. 12 - Explain the roles of troponin, tropomyosin, and...Ch. 12 - Which neurotransmitter is released by somatic...Ch. 12 - What is the motor end plate, and what kinds of...Ch. 12 - Prob. 16RQCh. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - The basic unit of contraction in an intact...Ch. 12 - The two functional types of smooth muscle are...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - Define muscle fatigue. Summarize factors that...Ch. 12 - Prob. 25RQCh. 12 - Prob. 26RQCh. 12 - Prob. 27RQCh. 12 - What is the role of the sarcoplasmic reticulum in...Ch. 12 - Compare and contrast: a. fast-twitch...Ch. 12 - Prob. 30RQCh. 12 - One way that scientists study muscles is to put...Ch. 12 - Prob. 32RQCh. 12 - On the basis of what you have learned about muscle...Ch. 12 - Prob. 34RQCh. 12 - Prob. 35RQ
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