Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 12.1, Problem 11CC
Summary Introduction
To determine: The factor that prevents the filaments from sliding back to the original position every time the head releases to bind to the next actin binding filament.
Introduction: The skeletal muscles are those muscles that are either connected to the skin or the skeleton or to both of the organs. These muscles help in movement of the skeletal system. It also helps in maintaining the body posture.
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Students have asked these similar questions
In the sliding filament theory of contraction, what prevents the filaments from sliding back to their original positions each time a myosin head releases to bind to next actin binding site?
Skeletal muscle cells undergo contractions based on a molecular mechanism involving:
1)the sliding of actin and myosin filaments past each other without any change in filament length
2) the shortening of actin filaments following direct interaction with myosin
3) dynamic instability of microtubules
4)none
What prevents the filaments from sliding back to their original position each time a myosin cross bridge detaches from actin?
Chapter 12 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 12.1 - Identify as many pairs of antagonistic muscle...Ch. 12.1 - Prob. 2CCCh. 12.1 - Prob. 3CCCh. 12.1 - Prob. 4CCCh. 12.1 - What are the three anatomical elements of a...Ch. 12.1 - What is the chemical signal at a neuromuscular...Ch. 12.1 - Prob. 7CCCh. 12.1 - Prob. 8CCCh. 12.1 - Prob. 9CCCh. 12.1 - Name an elastic fiber in the sarcomere that aids...
Ch. 12.1 - Prob. 11CCCh. 12.1 - Prob. 12CCCh. 12.1 - Prob. 13CCCh. 12.1 - According to the convention for naming enzymes,...Ch. 12.1 - Prob. 15CCCh. 12.1 - Prob. 16CCCh. 12.1 - Summation in muscle fibers means that the...Ch. 12.1 - Prob. 18CCCh. 12.1 - Which type of runner would you expect to have more...Ch. 12.1 - What is the response of a muscle fiber to an...Ch. 12.1 - Prob. 21CCCh. 12.2 - One study found that many world-class athletes...Ch. 12.3 - What is the response of a muscle fiber to an...Ch. 12.3 - Prob. 24CCCh. 12.3 - Prob. 25CCCh. 12.3 - Prob. 26CCCh. 12.3 - Prob. 27CCCh. 12.3 - Prob. 28CCCh. 12.3 - What happens to contraction if a smooth muscle is...Ch. 12.3 - Prob. 30CCCh. 12.3 - Prob. 31CCCh. 12.3 - Prob. 32CCCh. 12.3 - How can a neuron alter the amount of...Ch. 12.3 - Prob. 34CCCh. 12.3 - Prob. 35CCCh. 12 - The three types of muscle tissue found in the...Ch. 12 - Which two muscle types are striated?Ch. 12 - Which type of muscle tissue is controlled only by...Ch. 12 - Arrange the following skeletal muscle components...Ch. 12 - The modified endoplasmic reticulum of skeletal...Ch. 12 - Prob. 6RQCh. 12 - Prob. 7RQCh. 12 - List six proteins that make up the myofibrils....Ch. 12 - List the letters used to label the elements of a...Ch. 12 - Briefly explain the functions of titin and...Ch. 12 - During contraction, the __________ band remains a...Ch. 12 - Explain the sliding filament theory of...Ch. 12 - Explain the roles of troponin, tropomyosin, and...Ch. 12 - Which neurotransmitter is released by somatic...Ch. 12 - What is the motor end plate, and what kinds of...Ch. 12 - Prob. 16RQCh. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - The basic unit of contraction in an intact...Ch. 12 - The two functional types of smooth muscle are...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - Define muscle fatigue. Summarize factors that...Ch. 12 - Prob. 25RQCh. 12 - Prob. 26RQCh. 12 - Prob. 27RQCh. 12 - What is the role of the sarcoplasmic reticulum in...Ch. 12 - Compare and contrast: a. fast-twitch...Ch. 12 - Prob. 30RQCh. 12 - One way that scientists study muscles is to put...Ch. 12 - Prob. 32RQCh. 12 - On the basis of what you have learned about muscle...Ch. 12 - Prob. 34RQCh. 12 - Prob. 35RQ
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- What is the function of the sarcoplasmic reticulum in muscle cell contraction?arrow_forwardHow do actin and myosin interact in a sarcomere to bring about muscle contraction? What roles do ATP and calcium play?arrow_forwardFigure 38.37 Which of the following statements about muscle contraction is true? The power stroke occurs when ATP is hydrolyzed to ADP and phosphate. The power stroke occurs when ADP and phosphate dissociate from the myosin head. The power stroke occurs when ADP and phosphate dissociate from the actin active site. The power stroke occurs when Ca2+ binds the calcium head.arrow_forward
- In the diagram below, label the fine structure of a muscle, down to one of its myofibrils. Identify the basic unit of contraction in a myofibril.arrow_forwardWhat is the role of ATP and ATP hydrolysis in the cycle of actin-myosin association and disassociation that leads to muscle contraction?arrow_forwardWhat are the mechanisms for muscle contraction vs. relaxation in regards to myosin/thick filaments/thin filament movement? Is it true that if tropomysin blocks myosin sites, contraction ends and muscle relaxes?arrow_forward
- Why is myosin II the only myosin capable of producing contractile force?arrow_forwardCertain multi-headed myosins bind cooperatively to actin filaments. The binding interaction is mainly electrostatic in nature, so the presence of additional salt (ions) in solution can interfere with binding; ions will tend to associate with charged residues on the two proteins, blocking electrostatic attractions that would otherwise take place. Briefly describe the expected shape of the binding curve for one of these myosins, and what will happen to the shape when the salt concentration increases.arrow_forwardFor the following five events, which is the correct sequence that describes the excitation and contraction of a skeletal muscle fiber? 1. Tropomyosin shifts, exposing the myosin-binding sites on actin. 2. Calcium is released from the sarcoplasmic reticulum and binds to the troponin complex. 3. An action potential is propagated down the transverse tubules. 4. Cycles of myosin cross-bridge formation and breakdown cause the thin filaments to slide toward the center of the sarcomere. 5. An action potential in a motor neuron causes the axon to release acetylcholine, which triggers an action potential in a muscle fiber. 1 → 2 → 3 → 4 → 5 3 → 2 → 4 → 1 → 5 2 → 1 → 3 → 5 → 4 5 → 3 → 2 → 1 → 4 4 → 3 → 1 → 2 → 5arrow_forward
- Put these events that occur in skeletal muscle in the correct chronological sequence: 1. Opening of mechanically-gated ryanodine receptors (RyR) on the sarcoplasmic reticulum 2. Ca²+ binding to troponin to initiate contraction 3. Activation of voltage-gated dihydropyridine (DHP) receptor in the T-tubule 4. Na+ influx through ligand-gated ion channels on the motor end plate 4, 3, 2, 1 2, 1, 4, 3 3, 1, 2, 4 4, 3, 1, 2 3, 1, 4, 2arrow_forwardOne of the primary characteristics of all muscle tissue is contractility, the ability to shorten (contract) and lengthen (relax). You've identified the various components of a myofibril above. Now, use the table below to indicate what occurs to each band, line, or zone when the muscle contracts vs. relaxes. What occurs to this region / structure during contraction/relaxation? Region / Structure A-Band H-Band I-Band M-Line Z-Line Zone of Overlap Sarcomere No change Shortens Lengthens Muscle Contraction Muscle Relaxationarrow_forwardIn the process of muscle contraction, which of the following steps immediately precedes the sliding of tropomyosin causing exposure of actin? binding of acetylcholine to its receptor binding of calcium to troponin exocytosis of acetylcholine at NMJ binding of myosin head to actin's active site binding of ATP to the myosin headarrow_forward
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