Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 19P
14CO2 was bubbled through a suspension of liver cells that was undergoing gluconeogenesis from lactate to glucose. Which carbons in the glucose molecule would become radioactive?
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Chapter 12 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 12 - Prob. 1PCh. 12 - Methanol is highly toxic, not because of its own...Ch. 12 - Prob. 3PCh. 12 - Prob. 4PCh. 12 - Prob. 5PCh. 12 - Write balanced chemical equations for each of the...Ch. 12 - Prob. 7PCh. 12 - Prob. 8PCh. 12 - Prob. 9PCh. 12 - Prob. 10P
Ch. 12 - Some anaerobic bacteria use alternative pathways...Ch. 12 - Write a pathway leading from glucose to lactose in...Ch. 12 - Prob. 13PCh. 12 - Prob. 14PCh. 12 - Prob. 15PCh. 12 - How many ATP equivalents are consumed in the...Ch. 12 - Prob. 17PCh. 12 - Avidin is a protein that binds extremely tightly...Ch. 12 - 14CO2 was bubbled through a suspension of liver...Ch. 12 - Prob. 20PCh. 12 - Prob. 21PCh. 12 - Prob. 22PCh. 12 - Prob. 23PCh. 12 - 24. Glycogen synthesis and breakdown are regulated...Ch. 12 - Prob. 25PCh. 12 - Prob. 26PCh. 12 - Prob. 27PCh. 12 - Prob. 28PCh. 12 - 29 [1-14C] Ribose-5-phosphate is incubated with a...Ch. 12 - Prob. 30PCh. 12 - Prob. 31PCh. 12 - Prob. 32PCh. 12 - Prob. 33P
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- If a small amount of [1−14C] glucose is added to an aerobic yeast culture, where will the 14C label initially appear in citrate molecules?arrow_forwardIt is important to note that galactose is an important component of glyco- proteins. What is the effect on glycoprotein synthesis in case of galactosemic patients who are not given galactose in their diet? Explain this observation.arrow_forwardthis drug contains one or more building blocks derived from either ethylene oxide or epichlorohydrin.Identify the part of each molecule that can be derived from one or the other of the building block and propose structural formulas for the nucleophile(s) that can be used along with either ethylene oxide or epichlorohydrin to synthesize each molecule.arrow_forward
- Why "cellulose is composed of a long, branced chain of B-glucose subunits" is false?arrow_forwardLactate is a dead-end product in that its sole fate is to be converted back into glucose. Why then do cells bother to form lactate at all?arrow_forwardA glycogen polymer and an amylopectin polymer, each containing 100 monosaccharide subunits, are cleaved completely by an enzyme. How many individual glucose molecules are created during this process?arrow_forward
- Human insulin is prodụced as a recombinant protein in the yeast Saccharomyces cerevisiae The protein is extracted and purified for the treatment of diabetes -a $32 billion industry! For efficacy, insulin must be modified by the addition of oligosaccharyl (sugar) groups If you were a scientist working on this project, how would you isolate the glycosylated insulin from the un- glycosylated forms?arrow_forwardThe net charge on the most prevalent form of bisphosphoglycerate in blood is what?arrow_forwardCarbonyl cyanide 4- ( trifluoromethoxy ) phenylhydrazone (FCCP) is a proton ionophore : it enables protons to pass freely through membranes. Treatment of E. coli with FCCP prevents the accumulation of lactose in these cells. Explain.arrow_forward
- Fish living in environments such as the Arctic Ocean, wherewater temperatures are below the freezing point of theirblood, are able to survive because of so-called antifreezeglycoproteins. Suggest how these glycoproteins work.arrow_forwardThe OH group of the serine side chain (R-OH) can undergo dissociation to form R-O- and H+. However, the ratio of the protonated to unprotonated forms of this group at pH 7 is approximately 1,000,000 to 1. Calculate the pKa of the serine OH group.arrow_forwardTryptophan is not classified as a basic amino acid even though it has aheterocycle containing a nitrogen atom. Why is the N atom in the fivemembered ring of tryptophan not readily protonated by acid?arrow_forward
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