Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 12, Problem 26P
Interpretation Introduction

(a) Interpretation:

The metabolic significance of the statement "Only the liver form of pyruvate kinase is inhibited by alanine" should be explained.

Concept introduction:

The pyruvate kinase is the enzyme involved in the aerobic glycolysis process. It catalysis the glycolysis final step which involves the transfer of phosphate group from phosphoenolpyruvate to adenosine diphosphate, resulting formation of 1 molecule of pyruvate and ATP.

Interpretation Introduction

(b) Interpretation:

The metabolic significance of the statement "only gluconeogenic tissues contain appreciable levels of glucose -6-phosphatase" should be explained.

Concept introduction:

The enzyme glucose -6- phosphate is present in only those tissues which carry out gluconeogenesis.

It is a pathway that generates glucose from non-carbohydrate carbon substrates such as lactate and glycerol.

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