Concepts of Genetics (12th Edition)

12th Edition

ISBN: 9780134604718

Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian

Publisher: PEARSON

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations…

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Textbook Question

Chapter ST.3, Problem 1RQ

What is pharmacogenomics, and how does it differ from pharmacogenetics?

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Chapter ST Solutions

Concepts of Genetics (12th Edition)

Ch. ST.1 - What is the difference between innate immunity and...Ch. ST.1 - What evidence demonstrates that CRISPR-Cas is an...Ch. ST.1 - Prob. 3RQ Ch. ST.1 - Why was the type II CRISPR-Cas9 system of S....Ch. ST.1 - Prob. 5RQ Ch. ST.1 - What is a single guide RNA, and what role does it...Ch. ST.1 - What is the difference between nonhomologous...Ch. ST.1 - Prob. 8RQ Ch. ST.1 - Prob. 9RQ Ch. ST.1 - Prob. 1DQ

Ch. ST.1 - Prob. 2DQ Ch. ST.1 - What ethical and safety considerations must be...Ch. ST.1 - Recall (from Chapter 18) how miRNAs and the...Ch. ST.1 - Describe two different ways in which engineered...Ch. ST.1 - Consider the following human genetic diseases:...Ch. ST.1 - What are the different concerns about off-target...Ch. ST.2 - What is VNTR profiling, and what are the...Ch. ST.2 - Prob. 2RQ Ch. ST.2 - Describe capillary electrophoresis. How does this...Ch. ST.2 - What are the advantages and limitations of...Ch. ST.2 - Prob. 5RQ Ch. ST.2 - Explain why mitochondrial DNA profiling is often...Ch. ST.2 - Prob. 7RQ Ch. ST.2 - Describe the database system known as CODIS. What...Ch. ST.2 - Prob. 9RQ Ch. ST.2 - Prob. 10RQ Ch. ST.2 - Given the possibility that synthetic DNA could be...Ch. ST.2 - Prob. 2DQ Ch. ST.2 - If you were acting as a defense lawyer in a murder...Ch. ST.2 - The phenomena of somatic mosaicism and chimerism...Ch. ST.3 - What is pharmacogenomics, and how does it differ...Ch. ST.3 - Describe how the drug Herceptin works. What types...Ch. ST.3 - Prob. 3RQ Ch. ST.3 - Prob. 4RQ Ch. ST.3 - Prob. 5RQ Ch. ST.3 - Prob. 6RQ Ch. ST.3 - Why is it necessary to examine gene-expression...Ch. ST.3 - Prob. 8RQ Ch. ST.3 - Prob. 1DQ Ch. ST.3 - Prob. 2DQ Ch. ST.3 - How can we ensure that a patients privacy is...Ch. ST.3 - As gene tests and genomic sequences become more...Ch. ST.4 - How do genetically modified organisms compare with...Ch. ST.4 - Prob. 2RQ Ch. ST.4 - Prob. 3RQ Ch. ST.4 - Prob. 4RQ Ch. ST.4 - Describe the mechanisms by which the Cry proteins...Ch. ST.4 - Prob. 6RQ Ch. ST.4 - Prob. 7RQ Ch. ST.4 - Describe how plants can be transformed using...Ch. ST.4 - How do positive and negative selection techniques...Ch. ST.4 - Prob. 10RQ Ch. ST.4 - What are the laws regulating the development,...Ch. ST.4 - Do you think that foods containing GM ingredients...Ch. ST.4 - Prob. 3DQ Ch. ST.5 - What is gene therapy?Ch. ST.5 - Prob. 2RQ Ch. ST.5 - When treating a person by gene therapy, is it...Ch. ST.5 - Describe two ways that therapeutic genes can be...Ch. ST.5 - Explain how viral vectors can be used for gene...Ch. ST.5 - Prob. 6RQ Ch. ST.5 - Explain an example of a successful gene therapy...Ch. ST.5 - Prob. 8RQ Ch. ST.5 - Prob. 9RQ Ch. ST.5 - Prob. 10RQ Ch. ST.5 - Prob. 11RQ Ch. ST.5 - Prob. 1DQ Ch. ST.5 - Who should be treated by gene therapy? What...Ch. ST.5 - The lifetime costs for treatment of conditions...Ch. ST.5 - Should CRISPR-Cas or other techniques be used for...Ch. ST.5 - Prob. 5DQ Ch. ST.6 - What are RFLP markers and how were they used to...Ch. ST.6 - Why was information from Nancy Wexlers large...Ch. ST.6 - How do aggregates of mHTT protein form?Ch. ST.6 - Why are the results from the inducible mouse model...Ch. ST.6 - Based on the results from mouse models, is it...Ch. ST.6 - What do the results from creating transgenic mice...Ch. ST.6 - What steps lead from the binding of the mHTT...Ch. ST.6 - Summarize the approaches to therapy designed to...Ch. ST.6 - There are nine known progressive neurodegenerative...Ch. ST.6 - Prob. 2DQ Ch. ST.6 - Prob. 3DQ Ch. ST.6 - Why is there an inverse correlation between the...Ch. ST.6 - Discuss the ethical issues raised by the use a...

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What is pharmacogenomics, and how does it differ from pharmacogenetics?

Solution Summary: The author explains the term pharmacogenomics and its differences from the broader term, precision medicine, which examines a patient's genomic, proteomic, gene expression, and other molecular profiles.

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Chapter ST Solutions