Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 9.2, Problem 1CC
Summary Introduction
To describe: The process before the reassociation of β/γ dimer and α subunit with each other.
Introduction: GPCRs stands for G-protein-coupled-receptors and are present in cells of eukaryotes. It contains transmembrane segments which move back and forth through plasma membrane and interact with the intracellular G proteins.
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BIOC 384
Nuclear Receptor Signaling
Q8.3: Glucocorticoids are potent anti-inflammatory molecules that repress inflammation through transcriptional mechanisms. Beginning with inhalation of the asthma drug fluticasone, describe how this treatment reduces inflammation at the molecular level.
Q1. Explain why GDP cannot dissociate from the alpha subunit of the Trimeric G-protein even though
the receptor is activated by ligand binding and there is enough GTP for the exchange process.
Exercise 5
Membrane receptors are proteins that are incorporated in the cytoplasmic membrane of a cell, allowing the
detection of specific molecules such as (hormones, growth factor) and triggering a cascade of biochemical
Synthesis of protein
reactions.
The adjacent schema represents the steps of
the synthesis of these membrane receptors.
1. Label the structures from a to f.
In order to study the biosynthesis and
secretion of this protein (membrane
receptors), a solution containing radioactive
amino acid was injected in the blood of an
animal. Samples of certain cells were taken
at regular intervals of time. The intensity of
radioactivity was measured in different
cellular organelles.
2000
The table below represents the variations of the quantity of a membrane protein in different parts of the cell,
as function of time.
Time (min)
15
40
50
Structure X
26
12
2
1
Structure Z
0.
6.
10
6.
Structure Y
0.
10
24
2. Represent the obtained results in the form
3. 3.1. Analyze the obtained…
Chapter 9 Solutions
Biology
Ch. 9.1 - Figure 9.1 Response of a yeast cell to glucose....Ch. 9.1 - Prob. 1CSCh. 9.1 - Which type of signal, paracrine or endocrine, is...Ch. 9.1 - Prob. 3CCCh. 9.2 - Prob. 1CSCh. 9.2 - Prob. 2CSCh. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CSCh. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CC
Ch. 9.3 - In the case of signaling pathways involving...Ch. 9.5 - Prob. 1EQCh. 9.5 - Prob. 2EQCh. 9.5 - Prob. 3EQCh. 9.5 - Prob. 1CCCh. 9 - Prob. 1TYCh. 9 - Prob. 2TYCh. 9 - Prob. 3TYCh. 9 - Prob. 4TYCh. 9 - Prob. 5TYCh. 9 - The relay protein Ras is part of the EGF pathway...Ch. 9 - Prob. 7TYCh. 9 - Prob. 8TYCh. 9 - Prob. 9TYCh. 9 - Prob. 10TYCh. 9 - Prob. 1CQCh. 9 - Conceptual Questions What are the three stages of...Ch. 9 - Prob. 3CQCh. 9 - Prob. 1COQCh. 9 - Prob. 2COQ
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