Overview of Cell Signaling Pathways Q7.2: A first messenger molecule activates a receptor that stimulates Enzyme A, which synthesizes 100 second messenger molecules. In turn, each second messenger activates only one molecule of Enzyme B, which once activated, phosphorylates 100 molecules of Enzyme C that each phosphorylate 75 molecules of Enzyme D. In the last step, each Enzyme D phosphorylates 50 transcription factors.  How many transcription factors are phosphorylated in response to the first messenger binding to the receptor?  How many transcription factors would be phosphorylated if one copy of the Enzyme D gene were inactivated (heterozygous genotype) so that there were only half the number of functional Enzyme D molecules in the cell?  Explain.

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A: Answer) The similarity between APC in colon cancers and Rb in retinoblastomas is that both are…

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A: False statement about tumor suppressor genes.

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A: Solution - c is correct option- formation of stat heterodimer which act as transcription factor.

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Q: 19

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Q: 19. Explain the three main signal transduction mechanisms for GPCRs

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.