Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 9, Problem 24CTQ
How are the effects of paracrine signaling limited to an area near the signaling cells?
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Briefly explain how integrin inside-out and outside-in signaling is different structurally and functionally? (hint: explain what happened to ligand binding and conformation)
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In the B-acrenergic receptor signaling pathway where desensitization occurs, what
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The activity of the effector protein directly affects the activity of which protein in this pathway?
How would the presence of a GAP affect the desensitization process?
stimulate it
inhibit it
have no effect
What is the actual mechanism by which desensitization occurs?
the receptor is ubiquitinated
the hormone is phosphorylated
the hormone is degraded
the receptor is internalized
Chapter 9 Solutions
Biology 2e
Ch. 9 - Figure 9.8 HER2 is a receptor tyrosine kinase. In...Ch. 9 - Figure 9.10 In certain cancers, the GTPase...Ch. 9 - Figure 9.17 Which of the following statements...Ch. 9 - Figure 9.18 What advantage might biofilm...Ch. 9 - What property prevents the ligands of cell-surface...Ch. 9 - The secretion of hormones by the pituitary gland...Ch. 9 - Why are ion channels necessary to transport ions...Ch. 9 - Endocrine signals are transmitted more slowly than...Ch. 9 - A scientist notices that when she adds a small,...Ch. 9 - Where do DAG and IP3 originate? They are formed by...
Ch. 9 - What property enables the residues of the amino...Ch. 9 - Histamine binds to the H1 G-protein-linked...Ch. 9 - A scientist observes a mutation in the...Ch. 9 - What is the function of a phosphatase? A...Ch. 9 - How does NF-kB induce gene expression? A small,...Ch. 9 - Apoptosis can occur in a cell when the cell is...Ch. 9 - What is the effect of an inhibitor binding an...Ch. 9 - How does PKC’s signaling role change in response...Ch. 9 - A scientist notices that a cancer cell line fails...Ch. 9 - Which type of molecule acts as a signaling...Ch. 9 - Quorum sensing is triggered to begin when...Ch. 9 - A doctor is researching new ways to treat biofilms...Ch. 9 - What is the difference between intracellular...Ch. 9 - How are the effects of paracrine signaling limited...Ch. 9 - What are the differences between internal...Ch. 9 - Cells grown in the laboratory are mixed with a dye...Ch. 9 - Insulin is a hormone that regulates blood sugar by...Ch. 9 - The same second messengers are used in many...Ch. 9 - What would happen if the intracellular domain of a...Ch. 9 - If a cell developed a mutation in its MAP2K1 gene...Ch. 9 - What is a possible result of a mutation in a...Ch. 9 - How does the extracellular matrix control the...Ch. 9 - A scientist notices that a cancer cell line shows...Ch. 9 - What characteristics make yeasts a good model for...Ch. 9 - Why is signaling in multicellular organisms more...Ch. 9 - Pseudomonas infections are very common in hospital...
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- Give an example of contact-dependent signaling. What are some proteins involved?arrow_forwardWhat are the three main parts of a signaling pathway? Give a detailed specific example, such as how epinephrine signals for rapid digestion of glycogen in liver cells.arrow_forwardWhat key role does signal transduction play in the signaling process?arrow_forward
- Which components of the phosphoinositide signaling system are soluble and which are associated with the membrane?arrow_forwardHow does a receptor “know” which signaling molecules to bind?arrow_forwardList three ways in which a signal is amplified in a Gprotein-coupled receptor signaling pathway.arrow_forward
- What is PNS in the nervous system and how does it contribute to coordination in neural signaling?arrow_forwardCompare and contrast GPCR and RTK signaling. What role does GTP play in each? What role does phosphorylation play? How is each signal differently amplified? How do these two signaling types compare to steroid signaling with respect to gene activation?arrow_forwardExplain how a kinase cascade works. Why is this advantageous in the context of hormone signaling?arrow_forward
- What triggers the activation of G proteins? When triggered, what do G proteins do? Explain how a signal transduction process within a cell may be inactivated.arrow_forwardExplain three ways in which gradual increase in an extracellular signal can be sharpened by the target cell to produce an abrupt or nearly all-or-none response.arrow_forwardDescribe one way in which endocrine, paracrine, autocrine, and contact-dependent signaling pathways are similar to one another and one way in which they are different from one another.arrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license