Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Textbook Question
Chapter 9.1, Problem 2CC
Which type of signal, paracrine or endocrine, is likely to exist for a longer period of time? Explain why this longer existence is necessary.
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when kidney cells secrete low levels of oxygen in the blood they secrete erythropoietin. in this particular signaling pathway (response to low oxygen) the secretion of erythropoietin represents which step of the signal transdution process?
A cellular response occurs when a signal transduction pathway is activated in animals. Explain two forms of cellular responses that may arise as a result of paracrine or endocrine signaling.
What are the three main parts of a signaling pathway? Give a detailed specific example, such as how epinephrine signals for rapid digestion of glycogen in liver cells.
Chapter 9 Solutions
Biology
Ch. 9.1 - Figure 9.1 Response of a yeast cell to glucose....Ch. 9.1 - Prob. 1CSCh. 9.1 - Which type of signal, paracrine or endocrine, is...Ch. 9.1 - Prob. 3CCCh. 9.2 - Prob. 1CSCh. 9.2 - Prob. 2CSCh. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CSCh. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CC
Ch. 9.3 - In the case of signaling pathways involving...Ch. 9.5 - Prob. 1EQCh. 9.5 - Prob. 2EQCh. 9.5 - Prob. 3EQCh. 9.5 - Prob. 1CCCh. 9 - Prob. 1TYCh. 9 - Prob. 2TYCh. 9 - Prob. 3TYCh. 9 - Prob. 4TYCh. 9 - Prob. 5TYCh. 9 - The relay protein Ras is part of the EGF pathway...Ch. 9 - Prob. 7TYCh. 9 - Prob. 8TYCh. 9 - Prob. 9TYCh. 9 - Prob. 10TYCh. 9 - Prob. 1CQCh. 9 - Conceptual Questions What are the three stages of...Ch. 9 - Prob. 3CQCh. 9 - Prob. 1COQCh. 9 - Prob. 2COQ
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- Second-messenger systems ultimately bring about the desired cell response by inducing a change in the shape and function of particular designated intracellular proteins. (True or false?)arrow_forwardBriefly explain how integrin inside-out and outside-in signaling is different structurally and functionally? (hint: explain what happened to ligand binding and conformation)arrow_forwardHow is an extracellular signal converted to an intracellular signal in signal transduction? Give a specific example.arrow_forward
- The G protein coupled receptor (GPCR) pathway elicits diverse intracellular responses in different cells. The basic steps of GPCR signaling are outlined in this diagram. Which of the following statements correctly describes the process of GPCR signaling? The GPCR activation is reversible after the signal of the ligand diminishes. The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression. The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway. The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.arrow_forwardAMPK and mTOR can both be considered intracellular signal integrators. Explain this definition.arrow_forwardOne such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below: 1) Provide a brief explanation as to why ligand binding to proteins must be a reversible process. 2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins. 3) Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?arrow_forward
- Why do we need to identify and determine the function of every single molecule involved in cell signalling? Provide one concrete example of an application of an elucidated cascade of events in cell signalling. (The answer should be no less than 300 words)arrow_forwardWhat type of signal transduction is involved in signaling from hormones such as estrogen and testosterone? Explain the signal transduction pathway that occurs. 1. Is there a short term description for signal transduction, instead wrting multiple words to descripte the type of signal transduction? Can I just identify it as active signal transduction and inactive signal transduction. Based on my understanding, active singal transduction is for the fast react transdcution, while inactive signal transduction meanly refers the hormonal affacts on the system. 2. For Ion channels, specific enzymes are both involed activated and inactivated signal transduction?arrow_forwardIntracellular signaling pathways provide multiple opportunities for the amplification of a response to an extracellular signal. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a True Falsearrow_forward
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