Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 9.5CC
In the absence of oxygen, why is it necessary to ferment pyruvate to lactate or ethanol plus CO2?
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Why is pyruvate not oxidized to CO2 and H2O underanaerobic conditions?
Which of the following is NOT produced during the oxidative phase of the pentose phosphate shunt?
a
Ribulose-5-Phosphate
b
Glyceraldehyde-3-phosphate
c
CO2
d
NADPH
Pyruvate generated by glycolysis under anaerobic conditions is converted tolactate or ethanol. It may seem this is a waste of energy, but it is in factcritical to survival for cells exposed to oxygen limiting conditions. Explain whythis is true.
Chapter 9 Solutions
Becker's World of the Cell (9th Edition)
Ch. 9 - How are catabolic and anabolic pathways similar?...Ch. 9 - Prob. 9.2CCCh. 9 - Why do oxidation and reduction reactions always...Ch. 9 - How can glucose be oxidized in the absence of...Ch. 9 - In the absence of oxygen, why is it necessary to...Ch. 9 - Prob. 9.6CCCh. 9 - Prob. 1QCh. 9 - Why dont glycolysis (glucose to pyruvate) and...Ch. 9 - Why are the key regulatory enzymes in glycolysis...Ch. 9 - Why do cancer cells carry out high rates of...
Ch. 9 - High-Energy Bonds. When first introduced by Fritz...Ch. 9 - The History of Glycolysis. Following are several...Ch. 9 - Glycolysis in 25 Words or Fewer. Complete each of...Ch. 9 - Energetics of Carbohydrate Utilization. The...Ch. 9 - QUANTITATIVE Glucose Phosphorylation. The direct...Ch. 9 - Ethanol Intoxication and Methanol Toxicity. The...Ch. 9 - Propionate Fermentation. Although lactate and...Ch. 9 - QUANTITATIVE Glycolysis and Gluconeogenesis. As...Ch. 9 - Prob. 9.9PSCh. 9 - Youve Got Some Explaining to Do. Explain each of...Ch. 9 - Arsenate Poisoning. Arsenate (HAsO42) is a potent...Ch. 9 - Life Without Phosphofructokinase. Many bacteria do...Ch. 9 - Prob. 9.13PS
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- When 1 mole of fructose 1,6-bisphosphate is converted to 2 moles of pyruvate via the glycolysis pathway, the net formation of: *arrow_forwardOrganisms growing anaerobically cannot perform glycolysis for long without reducing the pyruvate from glycolysis into another compound, most commonly to lactate or to ethanol plus CO2. Which of the following provides the best explanation for sustaining anaerobic glycolysis? O Lactic acid has to be reduced to regenerate NADH Pyruvate has to be reduced to regenerate NADH Pyruvate has to be reduced to regenerate NAD+ Lactic acid has to be reduced to regenerate NAD+arrow_forwardConsider the steps of the krebs cycle and electron carrier chain and answer: a) How many ATPs are produced from 10 Pyruvato molecules? b) How many ATPs are produced from 12 Acetyl CoA molecules?arrow_forward
- The enzyme pyruvate dehydrogenase complex oxidises pyruvate by removing: He+ Ha+ H+ CI-arrow_forwarda) How many moles of ATP can be gained from the catabolism of the following substrates to pyruvate? 2 Mole mannose 2 Mole lactose mole glycerol. b) Name three metabolic processes in the cell that are enhanced and two that are inhibited in response to the hormone insulinarrow_forwarda) Using full chemical structures of substrates and products, draw the two possible pyruvate reduction pathways that regenerate NAD+ from NADH in the absence of oxygen gas. Give names of all compounds and enzymes involved. b) Draw the step in glycolysis that requires at least one of the above pathways to be functional in the absence of oxygen. Give names of all compounds and enzymes involved.arrow_forward
- Pyruvate can be converted into two different products depending on whether oxygen is readily available or not. Under conditions of strenuous activity (anaerobic) the product is: аcetyl CoA pyruvate lactate CO2arrow_forwardWhat happens in glycolysis if oxygen and pyruvic acid are absent and NADH + H+ cannot transfer its “picked-up” hydrogen to pyruvic acid?arrow_forwardThe condensation reaction catalyzed by ß-ketoacyl-ACP synthase synthesizes a four-carbon unit by combining a two-carbon unit and a three-carbon unit, with the release of CO₂. What is the thermodynamic advantage of this process over one that simply combines two two-carbon units? The reaction is reversible and does not require the input of ATP. The exergonic release of CO₂ drives the irreversible reaction in the direction of fatty acid synthesis. The release of CO₂ is endergonic and results in the production of ATP. The reaction is endergonic and requires the input of ATP.arrow_forward
- Why does pyruvate either form acoa or lactate? What are the conditions?arrow_forwardWhat is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex? Thymine pyroposphate lipoyllysine FAD NAD⁺arrow_forwardDuring aerobic respiration how many ATP molecules are produced by theoxidation of a single molecule of pyruvate?arrow_forward
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