Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 9, Problem 3CS

How much importance should we place on the results of ancestral genetic testing especially when these results have social, political, and legal implications? Is it ethical to determine one’s identity primarily or even partially on genetic considerations?

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Imagine that genetic technology advances to the point where the genetic profile of an individual can be easily obtained, and that we have a full understanding of how genes interact to influence our health. Based on this genetic information alone, how reliably do you think we would be able to predict a person's chance of getting a specific disease? Where do you think this type of genetic profiling would lead with respect to selection of offspring or genetic superiority?
"Ancestry tests" are sold by many companies. There are significant limitations to these tests. Why is this the case? High rates of gene flow between populations reduce the reliability with which any sequence can demonstrate membership in one particular population. Evaluating too few genetic loci, of which just a small number happen to be similar, can lead to the conclusion that individuals are much more genetically similar than they actually are. A DNA match between two individuals living today is not a match with an ancestor. Rather, it suggests that the two people may have inherited the DNA sequence from a common ancestor. all of these are limitations to "Ancestry tests" O High genetic variation among individuals within most populations makes it difficult to identify specific sequences that can reliably indicate membership in a population.
An important application of DNA fingerprinting is relationship testing. Persons who are related genetically have some bands or peaks in common. The number they share depends on the closeness of their genetic relationship. For example, an offspring is expected to receive half of his or her minisatellites from one parent and the rest from the other. The diagram shown here schematically illustrates traditional DNA fingerprints of an offspring, mother, and two potential fathers. In paternity testing, the offspring’s DNA fingerprint is first compared with that of the mother. The bands that the offspring have in common with the mother are depicted in purple. The bands that are not similar between the offspring and the mother must have been inherited from the father. These bands are depicted in red. Which male could be the father?

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Concepts of Genetics (12th Edition)

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Genetic Variation and Mutation | 9-1 GCSE Science Biology | OCR, AQA, Edexcel; Author: SnapRevise;https://www.youtube.com/watch?v=bLP8udGGfHU;License: Standard YouTube License, CC-BY