Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 6, Problem 24P
Indicate the role of each of the following in
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Describe the functions of the following proteins during DNA replication:
(i)
Polymerase I
(ii)
DnaA
(iii)
Telomerase
. Indicate the role of each of the following in DNA replication: (a) topoisomerase, (b) helicase, (c) primase,and (d) ligase.
In DNA replication, the role of topoisomerase is to
Question 11 options:
a)
"unzip" the double stranded DNA in front of DNA polymerase.
b)
maintain the single stranded DNA.
c)
supercoil the DNA after the replication fork has passed.
d)
relieve supercoil tension in the DNA in front of the replication fork.
Chapter 6 Solutions
Genetics: From Genes to Genomes
Ch. 6 - Griffith, in his 1928 experiments, demonstrated...Ch. 6 - Griffith, in his 1928 experiments, demonstrated...Ch. 6 - During bacterial transformation, DNA that enters a...Ch. 6 - Nitrogen and carbon are more abundant in proteins...Ch. 6 - If 30 of the bases in human DNA are A, a what...Ch. 6 - Which of the following statements are true about...Ch. 6 - Imagine you have three test tubes containing...Ch. 6 - What information about the structure of DNA was...Ch. 6 - A portion of one DNA strand of the human gene...Ch. 6 - When a double-stranded DNA molecule is exposed to...
Ch. 6 - A particular virus with DNA as its genetic...Ch. 6 - The underlying structure of DNA is very simple,...Ch. 6 - Prob. 13PCh. 6 - Bacterial transformation and bacteriophage...Ch. 6 - The CAP protein is shown bound to DNA in Fig....Ch. 6 - In Meselson and Stahls density shift experiments...Ch. 6 - When Meselson and Stahl grew E. coli in 15N medium...Ch. 6 - If you expose human tissue culture cells for...Ch. 6 - Draw a replication bubble with both replication...Ch. 6 - a. Do any strands of nucleic acid exist in nature...Ch. 6 - As Fig. 6.21 shows, DNA polymerase cleaves the...Ch. 6 - The bases of one of the strands of DNA in a region...Ch. 6 - Replicating structures in DNA can be observed in...Ch. 6 - Indicate the role of each of the following in DNA...Ch. 6 - Draw a diagram of replication that is occurring at...Ch. 6 - Figure 6.18 depicts Watson and Cricks initial...Ch. 6 - Researchers have discovered that during...Ch. 6 - A DNA synthesizer is a machine that uses automated...Ch. 6 - Bacterial cells were coinfected with two types of...Ch. 6 - A yeast strain with a mutant spo11- allele has...Ch. 6 - Imagine that you have done a cross between two...Ch. 6 - The Neurospora octad shown came from a cross...Ch. 6 - From a cross between e f g and e f g strains of...Ch. 6 - In Step 6 of Fig. 6.27, the resolvase enzyme...Ch. 6 - Figure 6.31shows four potential outcomes of...Ch. 6 - Each of the substrates for site-specific...Ch. 6 - Prob. 37PCh. 6 - Suppose that you could inject a wild-type mouse...Ch. 6 - C31 is a type of bacteriophage that infects...Ch. 6 - Cre is a recombinase enzyme encoded by a gene in...Ch. 6 - Like Cre/loxP recombination, site-specific...
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- Describe the functions of the following proteins during DNA replication: (i) Polymerase epsilon (ii) Polymerase alpha (iii) Dna A (iv) Telomerasearrow_forwardDescribe the functions of the following proteins during DNA replication: (i) Polymerase delta (ii) PCNA (iii) Telomerasearrow_forward(a) Eukaryotic DNA replication is more complex than prokaryotic replication. Give one reason why this should be so. (b) Why might eukaryotic cells need more kinds of DNA polymerases than bacteria?arrow_forward
- The central dogma of molecular biology states simply that DNA encodes RNA, and RNA encodes protein. For each of the following processes, describe, 1) where in the cell they occur, 2) one important protein (or protein containing complex) involved 3) the result of this process. DNA replication Where?) Protein?) Result?) Transcription Where?) Protein?) Result?) Splicing Where?) Protein?) Result?) Translation Where?) Protein?) Result?)arrow_forwardThe following diagram represents a DNA molecule that is undergoing replication. Draw in the strands of newly synthesized DNA and identify (a) the polarity of the newly synthesized strands, (b) the leading and lagging strands, (c) Okazaki fragments, and (d) RNA primers.arrow_forwardRegarding the process of DNA replication, is it correct to state that: (Only one statement is correct)* a) Nucleosomes are maintained during the replication process mediated by DNA polymerase b) The phosphodiester bonds that join the nitrogenous bases maintain the integrity of the DNA strands c) DNA polymerase requires a previously annealed deoxynucleotide to add the next monomer being synthesized d) The action of the helicase decreases the twist caused by the movement of the replication complex along the stretch of DNA e) The pre-replicative complex is assembled in the replication origin regions, being activated by proteolytic degradationarrow_forward
- In DNA replication, there are leading and lagging strands because A) DNA replication is conservative and a completely new DNA molecule must be made. B) DNA replication is semiconservative and each strand is copied simultaneously in opposite directions. C) the strands of DNA are parallel and are copied in the same direction simultaneously. D) one strand of DNA is copied faster than the other.arrow_forwardThe following diagrams represent DNA molecules that are undergoing replication. Draw in the strands of newly synthesized DNA and identify (a) the polarity of the newly synthesized strands, (b) the leading and lagging strands, (c) Okazaki fragments, and (d) RNA primers.arrow_forward10) Which of the following statements is false? A) Single stranded binding proteins help nucleotide bases pair during DNA replication. B) Topoisomerase prevents DNA from getting overwound during replication. C) DNA ligase connects Okazaki fragments during DNA replication. D) DNA helicase separates complementary strands of DNA during replication.arrow_forward
- Regarding the process of DNA replication, it is correct to state that: a) Nucleosomes are maintained during the DNA polymerase-mediated replication process b) The phosphodiester bonds that join the nitrogenous bases maintain the integrity of the DNA strands c) DNA polymerase requires a previously annealed deoxynucleotide to add the next monomer being synthesized. d) The action of the helicase decreases the twist caused by the movement of the replication complex along the stretch of DNA e)arrow_forwardDefine and indicate the significance of (a) Okazaki fragments,(b) DNA ligase, and (c) primer RNA during DNA replication.arrow_forward2- Direct DNA modifications are maintained mostly by Acetylation b) Methylation C) d) Hydroxylation None Leave blank ............ of cytosines?arrow_forward
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