Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 5, Problem 1Q

QUESTION: Why does the height of the spike get shorter after successive injections of ligand in Figure 5B-2a?

Chapter 5, Problem 1Q, QUESTION: Why does the height of the spike get shorter after successive injections of ligand in

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Actin alone Actin + Protein X -- Time [F-actin] (µM)
The top panel (a) of this figure shows the graded potential change (far right, upper, electrical trace) that results from ligand binding to the ligand gated Na+ channel. The bottom panel of this figure (b) shows a graded potential change (far right, lower, electrical trace) that results from ligand binding to a ligand gated Cl- channel. From this trace you know (Vm = -70 mV) 1. ECl- is -70 mV 2. ECl- is more negative than -70 mV (i.e., -80 mV) 3. ECl- is more positive than -70 mV (i.e., -60 mV)
Estimate the binding affi nity of a ligand for its receptor from the followingdata:
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