Biology
Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 41, Problem 2AC
Summary Introduction

To predict:

The symptoms of myasthenia gravis.

Introduction:

Myasthenia gravis is a neuromuscular disorder which causes weakness of skeletal muscle. It commonly affects muscles of eyes, face, and so on. This disorder occurs in a body when signals transmitted from nerve to muscle fiber are disrupted.

Summary Introduction

To explain: How neostigmine could help alleviate myasthenia gravis.

Introduction:

Myasthenia gravis is a neuromuscular disorder which causes weakness of skeletal muscle. It is a type of autoimmune disorder in which the immune system detects its own body cells as foreign cells and destroy them.

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A nerve conduction velocity test measures nerve conduction velocity. In this test, an electrical stimulus is applied to a peripheral nerve and the length of time it takes for the corresponding muscle to contract is measured. Because the length of the nerve from stimulus point to muscle and the time it takes for the muscle to contract are both known, NCV can be calculated. This test result is helpful in distinguishing between different types of pathologies. For example, a patient with muscle weakness is being tested by a physician. There are three possible sources of the weakness: Disease of the muscle itself such as muscular dystrophy. In this condition, normal muscle tissue is replaced by adipose tissue and the muscle becomes incapable of contraction. Disease at the neuromuscular junction (NMJ) such as myasthenia gravis. This condition is described in the Skeletal Muscle Histology exercise and results from damage to the acetylcholine receptors on the muscle end plate. Disease…
one treatment for myasthenia gravis is a medication that blocks the activity of acetylcholinesteras. suggest why this might be a succesful treatment
One treatment for myasthenia gravis is a medication that blocks the activity of acetylcholinesterase. Suggest why this might be a successful treatment.

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