Concept explainers
Effects of Dietary Fats on Lipoprotein Levels
Cholesterol that is made by the liver or that enters the body from food cannot dissolve in blood, so it is carried through the bloodstream in clumps called lipoprotein particles. Low-density lipoprotein (LDL) particles carry cholesterol to body tissues such as artery walls, where they can form deposits associated with cardiovascular disease. Thus, LDL is often called “bad” cholesterol. High-density lipoprotein (HDL) particles carry cholesterol away from tissues to the liver for disposal, so HDL is often called “good” cholesterol. In 1990, Ronald Mensink and Martijn Katan published a study that tested the effects of different dietary fats on blood lipoprotein levels. Their results are shown in FIGURE 3.2.
FIGURE 3.2 Effect of diet on lipoprotein levels. Researchers placed 59 men and women on a diet in which 10 percent of their daily energy intake consisted of cis fatty acids, trans fatty acids, or saturated fats.
The amounts of LDL and HDL in the blood were measured after three weeks on the diet; averaged results are shown in mg/dL (milligrams per deciliter of blood). All subjects were tested on each of the diets. The ratio of LDL to HDL is also shown.
An elevated risk of heart disease has been correlated with increasing LDL-to-HDL ratios. Which group had the highest LDL-to-HDL ratio?
Want to see the full answer?
Check out a sample textbook solutionChapter 3 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Additional Science Textbook Solutions
Human Anatomy & Physiology
Biology Illinois Edition (Glencoe Science)
Microbiology: An Introduction
Microbiology with Diseases by Body System (5th Edition)
Biology: Life on Earth with Physiology (11th Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
- Effects of Dietary Fats on Lipoprotein Levels Cholesterol that is made by the liver or that enters the body from food does not dissolve in blood, so it is carried through the bloodstream by lipoproteins. Low-density lipoprotein (LDL) carries cholesterol to body tissues such as artery walls, where it can form deposits associated with cardiovascular disease. Thus, LDL is often called bad cholesterol. Highdensity lipoprotein (HDL) carries cholesterol away from tissues to the liver for disposal, so HDL is often called good cholesterol. In 1990, Ronald Mensink and Martijn Katan published a study that tested the effects of different dietary fats on blood lipoprotein levels. Their results are shown in Figure 2.23. In which group was the level of LDL (bad cholesterol) highest?arrow_forwardEffects of Dietary Fats on Lipoprotein Levels Cholesterol that is made by the liver or that enters the body from food does not dissolve in blood, so it is carried through the bloodstream by lipoproteins. Low-density lipoprotein (LDL) carries cholesterol to body tissues such as artery walls, where it can form deposits associated with cardiovascular disease. Thus, LDL is often called bad cholesterol. Highdensity lipoprotein (HDL) carries cholesterol away from tissues to the liver for disposal, so HDL is often called good cholesterol. In 1990, Ronald Mensink and Martijn Katan published a study that tested the effects of different dietary fats on blood lipoprotein levels. Their results are shown in Figure 2.23. Figure 2.23 Effect of diet on lipoprotein levels. Researchers placed 59 men and women on a diet in which 10 percent of their daily energy intake consisted of cis fatty acids, trans fatty acids, or saturated fats. Blood LDL and HDL levels were measured after three weeks on the diet; averaged results are shown in mg/dL (milligrams per deciliter of blood). All subjects were tested on each of the diets. The ratio of LDL to HDL is also shown. Source, Mensink RP, Katan MB, Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. NEJM 323(7):43945. An elevated risk of heart disease has been correlated with increasing LDL-to-HDL ratios. Rank the three diets according to their predicted effect on cardiovascular health.arrow_forwardFatty acids are a component of fats but have distinct chemical difference apart from fats that would allow them to travel fairly freely in the aqueous environment of the blood stream. They don’t, however, and are transported with serum albumin. What about the chemistry of fatty acids makes it so that it might not be good to have a lot of them traveling freely in the bloodstream?arrow_forward
- Some foods naturally have high levels of the free amino acid. For example, parmesan cheese (1689 mg), tomato (246 mg), scallop (159 mg), corn (106 g), and shrimp (43 mg). Wheat protein (gluten) is typically comprised of 30-35% of this amino acid. People with celiac disease cannot metabolize gluten, but have no trouble with foods high in the natural amino acid or MSG. Why is this?arrow_forwardLipoproteins are relatively large, spherical clumps of protein and lipid molecules that circulate in the blood of mammals. They are like suitcases that move cholesterol, fatty acid remnants, triglycerides, and phospholipids from one place to another in the body. Given what you know about the insolubility of lipids in water, which of the four kinds of lipids would you predict to be on the outside of a lipoprotein clump, bathed in the fluid portion of blood?arrow_forwardIn dietary context, what is the difference between good and bad cholesterol? In dietary context, how do HDL and LDL differ in function?arrow_forward
- Lipoprotein particles are relatively large, sphericalclumps of protein and lipid molecules (see Figure 3.18)that circulate in the blood of mammals. They are likesuitcases that move cholesterol, fatty acid remnants, triglycerides, and phospholipids from one place to anotherin the body. Given what you know about the solubilityof lipids in water, which types of lipids would you predict to be on the outside of a lipoprotein clump, bathedin the water-based fluid portion of blood?arrow_forwardCholesterol that is made by the liver or that enters the body from food does not dissolve in blood, so it is carried through the bloodstream by lipoproteins. Low-density lipoprotein (LDL) carries cholesterol to body tissues such as artery walls, where it can form deposits associated with cardiovascular disease. Thus, LDL is often called "bad" cholesterol. High-density lipoprotein (HDL) carries cholesterol away from tissues to the liver for disposal, so HDL is often called "good" cholesterol. LDL levels were highest in the diet containing primarily ______. A. cis fatty acids B. saturated fats C. trans fatty acidsarrow_forwardDescribe TWO important roles of cholesterol that relates to human physiology with examples.arrow_forward
- When natural monounsaturated fats generally undergo the chemical process of partial hydrogenation, their fatty acid chains are converted into the following two forms: trans and saturated. O True Falsearrow_forwardCholic acid and deoxycholic acid function in solubilizing dietary lipids in the process of digestion and thereby help in their absorption in the intestine. These molecules belong to which category of lipids? triacylglycerols O glycerophospholipids O sphingolipids terpenes steroidsarrow_forwardExplain why HDL lipoprotein particle is called “good” cholesterol.arrow_forward
- Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage LearningBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning