Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 27, Problem 11CONQ
What is the difference between a neutral and an adaptive evolutionary process? Describe two or more examples of each. At the molecular level, explain how mutations can be neutral or adaptive.
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For each of the following examples, discuss whether the observed result is due to neutral mutations or mutations that have been acted on by natural selection, or both:
A. When comparing sequences of homologous genes, differences in the coding sequence are most common at the wobble base (i.e., the third base in each codon).
B. For a protein-encoding gene, the regions that encode portions of the polypeptide that are vital for structure and function are less likely to display mutations than other regions of the gene.
C. When comparing the sequences of homologous genes, introns usually have more sequence differences than exons.
What is a gene? Why are regulatory genes important to the evolutionary process? What is a mutation as defined in this course and readings. Are the end results of a mutation always "good" or always "bad"? Or is a mutation perhaps neither always good or always bad and could be "neutral or no effect" or "adaptive" in some situations? Does it depend on the gene, amino acid, protein, and case-by-case scenario? What genetic evidence suggests that humans are a part of a biological continuum with all life forms. Does the number of genes in a biological organism correlate, predict, or denote the complexity of the organism? Does the number of chromosomes in a biological organism correlate, predict, or denote the complexity of the organism?
Discuss the significance of mutations and explain the role of the environment in the evolutionary process. (Hint: Consider Lenski's study and what is demonstrated. Do not re-tell Lenski’s study)
Chapter 27 Solutions
Genetics: Analysis and Principles
Ch. 27.1 - A gene pool is a. all of the genes in a single...Ch. 27.1 - 2. In natural populations, most genes...Ch. 27.1 - A gene exists in two alleles designatedDandd. If...Ch. 27.1 - Prob. 4COMQCh. 27.2 - Which of the following is a factor that, by...Ch. 27.3 - 1. Darwinian fitness is a measure...Ch. 27.3 - 2. Within a particular population, darkly colored...Ch. 27.3 - 3. A population occupies heterogeneous...Ch. 27.3 - Prob. 4COMQCh. 27.4 - 1. Genetic drift is
a. a change in allele...
Ch. 27.4 - 2. Which of the following influences on genetic...Ch. 27.5 - Gene flow depends on a. migration. b. the ability...Ch. 27.6 - 1. Inbreeding is sexual reproduction between...Ch. 27.7 - The mutation rate is a. the likelihood that a new...Ch. 27.7 - 2. The transfer of an antibiotic resistance gene...Ch. 27.7 - Prob. 3COMQCh. 27 - 1. What is the gene pool? How is a gene pool...Ch. 27 - Prob. 2CONQCh. 27 - Prob. 3CONQCh. 27 - Prob. 4CONQCh. 27 - The termpolymorphismcan refer to both genes and...Ch. 27 - Prob. 6CONQCh. 27 - For a gene existing in two alleles, what are the...Ch. 27 - 8. In a population, the frequencies of two...Ch. 27 - The ability to roll your tongue is inherited as a...Ch. 27 - What evolutionary factors can cause allele...Ch. 27 - What is the difference between a neutral and an...Ch. 27 - Prob. 12CONQCh. 27 - Prob. 13CONQCh. 27 - Describe the similarities and differences among...Ch. 27 - 15. Is each of the following examples due to...Ch. 27 - Prob. 16CONQCh. 27 - Prob. 17CONQCh. 27 - 18. A group of four birds flies to a new location...Ch. 27 - 19. Describe what happens to allele frequencies as...Ch. 27 - With regard to genetic drift, are the following...Ch. 27 - When two populations frequently intermix due to...Ch. 27 - Two populations of antelope are separated by a...Ch. 27 - Prob. 23CONQCh. 27 - 24. Using the pedigree shown here, answer the...Ch. 27 - A family pedigree is shown here. A. What is the...Ch. 27 - 26. A family pedigree is shown here.
A. What is...Ch. 27 - Prob. 27CONQCh. 27 - Prob. 28CONQCh. 27 - 1. You will need to be familiar with the...Ch. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 3EQCh. 27 - Prob. 4EQCh. 27 - You will need to refer to question 2 in More...Ch. 27 - Prob. 6EQCh. 27 - Prob. 7EQCh. 27 - In the Grants study of the medium ground finch, do...Ch. 27 - 9. A recessive lethal allele has achieved a...Ch. 27 - Among a large population of 2 million gray...Ch. 27 - In a donor population, the allele frequencies for...Ch. 27 - Prob. 12EQCh. 27 - Prob. 13EQCh. 27 - Prob. 14EQCh. 27 - 15. What would you expect to be the minimum...Ch. 27 - Discuss examples of positive and negative...Ch. 27 - Discuss the role of mutation in the origin of...Ch. 27 - Prob. 3QSDC
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- In addition to physical traits, gene sequences can be used when comparing related species. Instead of looking for the presence or absence of a specific gene, you would look at the percent similarity between the same gene in two or more species. Therefore, it is important to select a gene that contains a similar DNA gene sequence in each of the species being compared. Certain genes are involved in processes that are required for basic cellular function. As these processes are critical to cell function, the genes that regulate them are highly conserved, meaning that they have remained essentially unchanged over time. Glycolysis is one such process that is critical for cellular metabolism. Glycolysis involves converting glucose into pyruvate in order to generate ATP, the energy currency of the cell. Because glycolysis is an essential process for all species, the genes involved are therefore highly conserved. You will be looking at similarities among different taxa of the highly conserved…arrow_forwardYou are collaborating with a cool new local brewery on an experiment with one of their strains Saccharomyces cerevisiae, brewer’s yeast. You decide to apply what you learned in Evolution to create a mutation accumulation (MA) line to see if the patterns of mutation in their strain of S. cerevisiae follow patterns seen in other species. Which of the following best describes an actual result you observe form studying the mutation accumulation (MA) lines you created? a. Beneficial mutations occur far less frequently than deleterious mutations do. b. The neutral mutations had a greater effect on fitness compared to other mutation types. c. Most of the mutations that occur are the result of large chromosomal rearrangements. d. Of all possible mutation types, deleterious mutations are the most common mutation.arrow_forwardIn the replica plate experiment, it shows that mutations are random. However, certain environmental stresses (such as high temperature, high salt, and low pH) can increase the mutation rate. QUESTIONS: Does increasing the mutation rate increase the probability that an individual mutation will be adaptive?arrow_forward
- Steven Frank and Laurence Hurst argued that a cytoplasmically inherited mutation in humans that has severe effects in males but no effect in females will not be eliminated from a population by natural selection because only females pass on mtDNA (S. A. Frank and L. D. Hurst. 1996. Nature 383:224). Using this argument, explain why males with Leber hereditary optic neuropathy are more severely affected than females.arrow_forward10) Two processes that take place within a cell are shown here. Which of these statements correctly identify the processes and their outcomes? Select ALL that apply. A) Both processes increase genetic variation. B) Both processes can produce new phenotypes in an organism. C) Process II occurs randomly while process I is predictable. D) Process I is beneficial to the organism while process II is detrimental. E) Only process I can provide the basis for natural selection acting on phenotypes. Not Gradedarrow_forwardAlbinism in humans can be caused by mutations in any one of several different genes. This situation, in which the same phenotype may result from variation in several different genes, is referred to as genetic heterogeneity. Is genetic heterogeneity common? Are most genetic traits in humans the result of variation in a single gene, or are there many genetic traits that result from variation in several genes, as albinism does?arrow_forward
- Discuss the role of mutation in the origin of genetic polymorphisms. Suppose that a genetic polymorphism involves two alleles at frequencies of 0.45 and 0.55. Describe three different scenarios to explain these observed allele frequencies. You can propose that the mutations that produced the polymorphism are neutral, beneficial, or deleterious.arrow_forwardWyckoff et al. (2000. Nature 403:304-309) have proposed that some human male reproductive-associated genes have evolved by natural selection and not by neutral evolution. Part of the DNA sequence results of their study is shown below. Which gene(s) did seem to evolve by natural selection? Note: dn = number of substitutions per non-synonymous (replacement) sites and ds = number of substitutions per synonymous (silent) sites. dn ds Acrosin-Trypsin 0.138 0.064 Protamine 1 0.133 0.046 SRY 0.055 0.090 Histone H1 (testicular) 0.055…arrow_forwardMany animals have the p53 gene that makes a protein that regulates the cell cycle and helps prevent the formation of cancer cells. The table below shows the percentage of p53 gene sequences that the 4 species have when compared to humans. Species Percentage of p53 Gene Sequence Similar to Human Human 100 Horse 60.7 Fruit Fly 15.5 Rat 76.8 Pig 81.3 Which organism in the table is most closely related to humans based on this data? pig horse fruit fly rat 0 0 0 0arrow_forward
- Recent studies reveal that certain areas of the DNA are less prone to DNA mutations and that mutations may not be random after all. In a study on Arabidopsis thaliana, important genes that are involved in cell growth and expression have been observed to have low mutation rates. What is a possible implication of this observation in evolution?arrow_forwardGenes control thousands of different traits in plants. These genes can be selected for during natural selection (which drives evolution) and artificial selection (which drives domestication of dogs, crops, etc). During the domestication of modern tomato, describe the traits that were and were not selected. In your own words, describe in 2-3 sentences why domesticated tomatoes bought at a grocery store are lackluster compared to heirlooms or wild tomatoes. What are a few genetic and non-genetic traits that control tomato flavor and taste?arrow_forwardThe use of nucleotide sequence data to measure genetic variability is complicated by the fact that the genes of higher eukaryotes are complex in organization and contain 5′ and 3′ flanking regions as well as introns. Researchers have compared the nucleotide sequence of two cloned alleles of the g-globin gene from a single individual and found a variation of 1 percent. Those differences include 13 substitutions of one nucleotide for another and 3 short DNA segments that have been inserted in one allele or deleted in the other. None of the changes takes place in the gene’s exons (coding regions). Why do you think this is so, and should it change our concept of genetic variation?arrow_forward
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