Concept explainers
Interpretation:
How the energy releasing steps of glycolysis are reversed in gluconeogenesis has to be explained.
Concept Introduction:
Glycolysis: This is the
Gluconeogenesis: This process of synthesis of glucose or glycogen from non-carbohydrate sources is called gluconeogenesis.
Substrate for gluconeogenesis
- Glycogenic amino acid
- Glycerol
- Pyruvate
- Lactate
- Intermediate of TCA cycle.
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
- Describe the coordinated regulation of glycolysis and gluconeogenesis.arrow_forwardList all of the regulatory enzymes from both Glycolysis and Gluconeogenesis, and under each, list the (-) inhibitors and the (+) activators.arrow_forwardWhy is it important that gluconeogenesis is not the exact reversal of glycolysis?arrow_forward
- Define Glycolysis and Gluconeogenesis. How GLYCOLYSIS and GLUCONEOGENESIS does reciprocally regulated in the body? Explain it.arrow_forwardIdentify the two stages of the pentose phosphate pathway, and explain how the pathway is coordinated with glycolysis and gluconeogenesis.arrow_forwardc) Cooperation between glycolysis and gluconeogenesis is important to ensure the glucose-subjected energy demands of specific cells are met. Explain this statement.arrow_forward
- Is the statement much of the regulation of gluconeogenesis a result of the inhibition of glycolysis incorrect or correct?arrow_forwardIn simple terms explain why gluconeogenesis is important?arrow_forwardExplain why pyruvate cannot be converted to glucose in an exact reverse of the glycolysis pathway.arrow_forward
- How many steps in gluconeogenesis are not the exact reversal of the steps in glycolysis? What kind of conversion of substrate to product does each involve? What is the common theme in each of these reactions?arrow_forwardHow are the irreversible reactions of glycolysis bypassed in gluconeogenesis?arrow_forwardPlease explain how glycolysis is linked to the CAC.arrow_forward
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