Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 20.1, Problem 3COMQ
A key difference between the original Holliday model and the double-strand break model is the way that
a. the DNA strands are initially broken.
b. branch migration occurs.
c. a heteroduplex is formed.
d. resolution occurs.
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All of the following statements about telomerase are correct except:
A. the RNA component acts as a template for the synthesis of a segment of DNA.
B. it adds telomeric repeats to the 5'-ends of the DNA strands.
C. it provides a mechanism for replicating the ends of linear chromosomes.
D. it recognizes a G-rich single strand of DNA
E. it is a reverse transcripcase.
What observations are consistent with the conclusion that DNA serves as the genetic material in eukaryotes?
Select the four correct statements.
a. DNA content and ploidy in various cell types( sperm and somatic cells) are related
b. DNA is found to be the only macromolecule in eukaryotes that has different subunits.
c. Gene transfer is a direct evidence as it has been facilitated by recombinant DNA techniques.
d. The correlation of the action and absorption spectra of ultraviolet light support the interpretation that DNA is a genetic material.
e. DNA is shown to be present in ribosomes, matrix, and nucleus, where genetic function is performed.
f. DNA is shown to be present in mitochondria, chloroplasts, and nucleus, where genetic function is performed.
How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair system:
A.recognizes fully methylated DNA and replaces the purine.
B. recognizes partially methylated DNA and replaces the pyrimdine.
C. Recognizes partially methylated DNA and fixes the methylated strand
D. Recongnizes partially methylated DNA and fixes the nonmethylated strand
E. Makes no distiction between strands, and therefore fixes the wrong base 50% of the time
Chapter 20 Solutions
Genetics: Analysis and Principles
Ch. 20.1 - 1. Homologous recombination refers to the exchange...Ch. 20.1 - During the molecular process of homologous...Ch. 20.1 - 3. A key difference between the original Holliday...Ch. 20.1 - Which of the following mechanisms can cause gene...Ch. 20.2 - 1. During site-specific recombination that occurs...Ch. 20.2 - Prob. 2COMQCh. 20.3 - Which of the following types of transposable...Ch. 20.3 - Prob. 2COMQCh. 20.3 - Prob. 3COMQCh. 20 - 1. Describe the similarities and differences...
Ch. 20 - Prob. 2CONQCh. 20 - 3. Which steps in the double-strand break model...Ch. 20 - Prob. 4CONQCh. 20 - Prob. 5CONQCh. 20 - Prob. 6CONQCh. 20 - Prob. 7CONQCh. 20 - 8. What is gene conversion?
Ch. 20 - Make a list of the differences between the...Ch. 20 - Prob. 10CONQCh. 20 - Prob. 11CONQCh. 20 - 12. According to the double-strand break model,...Ch. 20 - What type of DNA structure is recognized by RecG...Ch. 20 - Briefly describe three ways that antibody...Ch. 20 - 15. Describe the functions of the RAG1 and RAG2...Ch. 20 - According to the scenario shown in Figure 20.7,...Ch. 20 - Prob. 17CONQCh. 20 - Prob. 18CONQCh. 20 - 19. Why does transposition always produce direct...Ch. 20 - 20. Which types of TEs have the greatest potential...Ch. 20 - Prob. 21CONQCh. 20 - 22. Let’s suppose that a species of mosquito has...Ch. 20 - This chapter describes different types of TEs,...Ch. 20 - Prob. 24CONQCh. 20 - Prob. 25CONQCh. 20 - 26. What is the difference between an autonomous...Ch. 20 - 1. Briefly explain how McClintock determined that...Ch. 20 - The work of McClintock showed that the presence of...Ch. 20 - 3. In your own words, explain the term transposon...Ch. 20 - Prob. 4EQCh. 20 - 5. Gerald Rubin and Allan Spradling devised a...Ch. 20 - Make a list of the similarities and differences...Ch. 20 - Prob. 2QSDCCh. 20 - Prob. 3QSDC
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- Which of the following statements is not true? Explain why. A. A DNA strand can serve as a template strand on many occasions. B. Following semiconservative DNA replication, one strand is a newly made daughter strand and the other strand is a parental strand. C. A DNA double helix may contain two strands of DNA that were made at the same time. D. A DNA double helix obeys the AT/GC rule. E. A DNA double helix could contain one strand that is 10 generations older than its complementary strand.arrow_forwardThe diagram illustrating the polymerase chain reaction (PCR) technique is provided below. How does the number of copies of the DNA region being amplified change at the end of each cycle of the polymerase chain reaction? Group of answer choices a. The number of copies triples (or triplicates). b. The number of copies does not change. c. The number of copies quadruples (or quadruplicates). d. The number of copies doubles (or duplicates). e. The number of copies halves.arrow_forwardWhich of the following statements is FALSE regarding the molecular mechanism for DNA polymerases? A. The active site contains 2 divalent metal ions B. A single stranded DNA template is required C. The enzyme can only attach a new deoxynucleotide to the 5’ end of a growing chain D. The 3’OH on the deoyxyribose ring attacks a phosphate of a dNTP to produce a new phosophodiester bond E. None of the above (all are true statements)arrow_forward
- Which of the following statements is TRUE concerning the synthesis of the leading and lagging strands of DNA in prokaryotic cells? a. O b. The leading strand is synthesized by one polymerase III continuously, and the lagging strand is synthesized by several molecules of DNA polymerase III. d. The leading and lagging strands are synthesized at the same time by the one DNA polymerase I. O c. The leading and lagging strands are synthesized at the same time by the one DNA polymerase III. The leading strand is synthesized by one polymerase III, and the lagging strand is synthesized by DNA polymerase I.arrow_forwardWhich proteins are responsible for the unwinding of the double-stranded DNA during relication? A. Primases. B. Lyases. C. Helicases D. Topoisomerases E. Ligasesarrow_forwardDefine the following terms: a. processivity b. replisome c. exonuclease d. DNA ligase e. repliconarrow_forward
- In Noll’s experiment to test the beads-on-a-string model, exposure of nuclei to a low concentration of DNase I resulted ina. a single band of DNA with a size of approximately 200 bp.b. several bands of DNA in multiples of 200 bp.c. a single band of DNA with a size of 100 bp.d. several bands of DNA in multiples of 100 bparrow_forwardWould it be possible to start synthesizing the daughter DNA strand without assembling the RNA primer first? Why? Why not? A. Yes, because the 3' OH is already present in the DNA strand which will be used as a template. B. No, because the RNA primer which contains the free 5' PO4 in its ribose will not be synthesized by primase. C. Yes, because the 5' PO4 is already present in the DNA strand which will be used as a template. D. No, because the RNA primer which contains the free 3' OH in its ribose has to be synthesized by primase first.arrow_forwardWould it be possible to start synthesizing the daughter DNA strand without assembling the RNA primer first? Why? Why not?arrow_forward
- Which of the following molecules helps relieve the tension of unwinding parental DNA strands, by breaking DNA and rejoining it before it is replicated? a. Primase b. Single-stranded binding proteins c. Helicase d. Topoisomerasearrow_forwardMismatch repair in E. coli distinguishes between old and new strands of DNA on the basis of a. differences in the base composition of the two strands. b. modification of histone proteins. c. base analogs on the new strand. d. methyl groups on the old strand.arrow_forwardWhat is Sanger sequencing? Why do we use ddNTP? How to read a DNA sequence gel? c. What is a cDNA seq (RNA seq)? d. What is the main difference between a genomic and a transcriptome study?arrow_forward
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