Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 20, Problem 2CONQ
Summary Introduction

To review:

The formation of heteroduplex in sister chromatid exchange during the occurrence of branch migration. The occurrence of gene conversion during an exchange of sister chromatid.

Introduction:

Homologous recombination is a process of exchange of nucleotide sequences between two similar DNA (deoxyribonucleic acid) molecules. This process helps in repairing the breaks, which are harmful and occur on both the DNA strands. It is a tool of genome engineering.

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The molecular mechanism of SCE is similar to homologousrecombination between homologs except that the two segmentsof DNA are sister chromatids instead of homologous chromatids.If branch migration occurs during SCE, will a heteroduplex beformed? Explain why or why not. Can gene conversion occurduring sister chromatid exchange?
What is a sister chromatid? Are sister chromatids genetically similar or identical? Explain
Describe the similarities and differences between homologousrecombination involving sister chromatid exchange (SCE) and thatinvolving homologs. Would you expect the same types of proteinsto be involved in both processes? Explain.

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Genetics: Analysis and Principles

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genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license