Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 20.2, Problem 2COMQ
Summary Introduction

Introduction:

Antibodies are also known as immunoglobulins, which arelarge proteinsthat are produced by plasma cells. These antibodies are used by the immune system for killing and removing pathogens, which might be bacteria or virus, and provide protection to the organism from infection.

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Explain how each of the following processes contributes to antibody diversity. a. Somatic recombination b. Junctional diversity c. Hypermutation
The phenomenon of allelic exclusion ensures that B cells a. use only one V, D, and J segment during somatic recombination b. express only one type of heavy chain and one type of light chain c. do not undergo alternative splicing until cell proliferation commences d. do not secrete antibody until antigen is encountered e. carry out affinity maturation directed at heavy chains and not light chains f. derived from B-cell lymphomas are heterogeneous.
Explain how Somatic recombination  contributes to antibody diversity.

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Genetics: Analysis and Principles

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genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license