Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 2, Problem 7P
Interpretation Introduction

Interpretation:

The structure of the dipeptide Gly-His at pH 5.5 and pH 7.5 should be drawn.

Concept introduction:

The ionization of an amino acid depends on the pH. In acidic pH, both amino group and carboxylate group are protonated. When pH increases, the carboxylic acid is the first to deprotonate. At higher pH’s the protonated form of amino group also lose a proton.

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