Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 2, Problem 15P
Interpretation Introduction

(a)

Interpretation:

The length of tropomyosin needs to be determined.

Concept introduction:

Amino acids are organic compounds containing amino as well as carboxylic acid groups. These groups are common in all amino acids. The difference in all amino acids is different R groups. The general representation of an amino acid is as follows:

H2NCH(R)COOH

Here, R group is different for different amino acids. This group can be acidic, basic or neutral.

Interpretation Introduction

(b)

Interpretation:

For the motif, longest dimension needs to be determined.

Concept introduction:

The hairpin loop is formed when 2 regions having the same strands but complementary in the sequence of nucleotide results in base pairing to from a double helix ending in an unpaired loop.

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Students have asked these similar questions
(a) Tropomyosin, a 70-kDa muscle protein, is a two-stranded α -helical coiled coil. Estimate the length of the molecule. (b) Suppose that a 40- residue segment of a protein folds into a two-stranded antiparallel β structure with a 4-residue hairpin turn. What is the longest dimension of this motif?
. Consider a small protein containing 101 amino acid residues. The protein will have 200 bonds about which rotation can occur. Assume that three orientations are possible about each of these bonds. (a) Based on these assumptions, about how many random-coil conforma- tions will be possible for this protein? (b) The estimate obtained in (a) is surely too large. Give one reason why.
i. A schematic structure of the subunit of hemerythrin (an oxygen-binding protein from invertebrate animals) is shown to the right. (a) It has been found that in some of the a-helical regions of hemerythrin, about every third or fourth amino acid residue is a hydrophobic one. Suggest a structural reason for this finding. (b) What would be the effect of a mutation that placed a proline residue at point A in the structure?
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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license