To determine: The forces that promote glomerular filtration.
Introduction: There is cluster of capillaries and small blood vessels at the end of the kidney tubules. This is known as glomerulus. Glomerulus filters the large sized substances from the blood.
To determine: The force that opposes the glomerular filtration.
Introduction: Nephrons are the basic functional unit of kidneys. They are responsible for filtration of waste from the body. Each nephron consists of Bowman’s capsule containing glomerulus, proximal convoluted tubule, and distal convoluted tubule and collecting ducts.
To determine: The meaning of term net driving force.
Introduction: Human beings have a pair of the kidneys. The essential function of kidneys is to reabsorb water, sodium, and other nutrients from the filtrate to prevent the elimination of useful material from the body. Most plasma proteins and blood cells are excluded through the glomerular capsule.
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Human Physiology: An Integrated Approach (8th Edition)
- How net filtration pressure (NFP) depends directly upon the algebraic sum of four variables?arrow_forwardAtrial Natriuretic Peptide helps to reduce overall blood pressure in a variety of ways. One way is by increasing Glomerular Filtration Rate. a. Why/how would increasing GFR cause decreased blood pressure? b. To increase GFR, would Atrial Natriuretic Peptide cause constriction or dilation of afferent arterioles at the kidneys? The efferent arterioles?arrow_forward24. Measurements are made of the renal tubular fluid concentration of various substances along the length of the proximal tubule and plotted as the tubular fluid to plasma concentration ratio (TF/P). As these substances are reabsorbed along with water, the following profiles are obtained. (All substances are freely filtered at the glomerulus, the TF/P = 1 at the glomerulus.) Glucose is represented by which of the following curves? OA) [Tubular fluid] [Plasma] OB) 3.0- 2.0- 1.0- 0 B O C) E 25 50 75 Proximal tubule length (%) OD) 100 OE)arrow_forward
- In a canine expt, a dog’s filtered load of sodium (Na+) in an isolated pump-perfused kidney is found to be 15mmol/min. How much Na+would you predict remains in the tubule at the end of the proximal tubule? Explain your reasoning.arrow_forwardGlomerular filtration is affected by forces that oppose and promote filtration. What are these forces and explain the theory behind net filtration pressure?arrow_forwardThe process of hydrogen ion secretion in the proximal convoluted tubule occurs via which of the following mechanisms? Choose from the following: (A) hydrogen ions diffuse out of the glomerular filtrate of the proximal convoluted tubule, through extracellular fluid and into the peritubular blood (B) carbon dioxide diffuses into the proximal convoluted tubule cell from peritubular capillary blood; undergoes a chemical reaction to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ion diffuses into the glomerular filtrate of the proximal convoluted tubule (C) hydrogen ions diffuse out of the peritubular capillary blood, through extracellular fluid and into the filtrate of the proximal convoluted tubule (D) carbon dioxide diffuses into the proximal convoluted tubule cell from the glomerular filtrate; undergoes a chemical reacdtion to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ions diffuse into the peritubular bloodarrow_forward
- During the maximal water diuresis, the ratio of the tubular fluid to plasma osmolarity is greater than 1.0 in which of the following? (A) The bend of the loop of Henle (B). Bowman Space (C) The collecting duct (D) The distal renal tubule (E) The proximal convoluted renal tubulearrow_forwardDiabetes insipidus (DI) is a condition where the action of antidiuretic hormone (vasopressin) is inhibited. If normal urine concentration is 300 mOsm/L, what would you expect the urine concentration to be of a patient with DI?arrow_forwardThis component of the filtration membrane is formed by which of the following Choose from the following: (A) basal lamina of the podocytes (B) basal lamina of the fenestrated endothelium (C) reticular lamina of the podocytes (D) reticular lamina of the fenestrated endothelium (E) A and B (F) B and C (G) C and Darrow_forward
- This diagram illustrates which of the following Choose from the following: (A) secretion of hydrogen via Na+/H+ exchange ions by the proximal convoluted tubule (B) reabsorption of bicarbonate ions by intercalated cells (A) in the collecting duct (C) secretion of H+ by H+K+/ATPase pumps in the intercalated cells (A) in the collecting duct (D) A and B (E) all of the abovearrow_forwardSodium ion reabsorption from the filtrate into peritubular blood across the cells of this component of the nephron (marked by the black asterisk) Choose from the following: (A) is regulated by the binding of the hormone aldosterone (B) is not regulated by any hormone, but is determined by sodium ion concentration and filtrate flowarrow_forwardUrine creatinine: 180 mg/dL . Plasma creatinine: 2.3 mg/dL . Urine output: 1.6 mL/mi Creatinine Clearance (C) = (Urine Creatinine × Urine Flow Rate) / Plasma Creatinine What is Carrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning