Concept explainers
Read the box on hemodialysis on p. 603 and see if you can create a model system that would work for dialysis. Draw two compartments (one to represent blood and one to represent dialysis fluid) separated by a semipermeable membrane. In the blood compartment, list normal extracellular fluid solutes and their concentrations (see the table with normal values of blood components inside the back cover of this book). What will happen to the concentrations of these solutes during kidney failure? Which of these solutes should you put in the dialysis fluid, and what should their concentrations be? (Hint: Do you want diffusion into the dialysis fluid, out of the dialysis fluid, or no net movement?) How would you change the dialysis fluid if the patient was retaining too much water?
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Human Physiology: An Integrated Approach (8th Edition)
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