Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 19, Problem 13RQ
Summary Introduction
To determine: The solute present in the body that is used to approximate GFR in humans.
Introduction: GFR stands for glomerular filtration rate. It is the volume of fluid that is filtered into Bowman’s capsule in a unit time. The average value of GFR is 125 mL/min or 180 L/day.
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Extrinsic and intrinsic controls of GFR serve two different purposes. What are they?
If Glomerular filtration rate (GFR) is 125 mL/min, how much GF will be produced in a day?
180,000 mL?
If the Tm for a particular amino acid is 220 mg/100 ml and the concentration of that
amino acid in the blood is 130 mg/100 ml, the amino acid will
Question options:
a) not appear in the urine because it is too large to be filtered
b) be actively secreted into the filtrate
d) be completely reabsorbed by the tubule cells
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Chapter 19 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 19.1 - Ion regulation is a key feature of kidney...Ch. 19.1 - What happens to the force of cardiac contraction...Ch. 19.2 - If net filtration out of glomerular capillaries...Ch. 19.2 - If net reabsorption into peritubular capillaries...Ch. 19.3 - Name one way in which filtration and secretion are...Ch. 19.3 - A water molecule enters the renal corpuscle from...Ch. 19.3 - Prob. 7CCCh. 19.4 - Why is the osmotic pressure of plasma in efferent...Ch. 19.4 - If a hypertensive persons blood pressure is...Ch. 19.4 - If systemic blood pressure remains constant but...
Ch. 19.4 - A person with cirrhosis of the liver has...Ch. 19.7 - If plasma creatinine = 1.8 mg/100 mL plasma, urine...Ch. 19 - List and explain the significance of the five...Ch. 19 - List and explain the six major kidney functions.Ch. 19 - At any given time, what percentage of cardiac...Ch. 19 - Prob. 4RQCh. 19 - Arrange the following structures in the order that...Ch. 19 - Name the three filtration barriers that solutes...Ch. 19 - Prob. 7RQCh. 19 - What does the abbreviation GFR stand for? What is...Ch. 19 - Identify the following structures, then explain...Ch. 19 - In which segment of the nephron does most...Ch. 19 - Match each of the following substances with its...Ch. 19 - Prob. 12RQCh. 19 - Prob. 13RQCh. 19 - Prob. 14RQCh. 19 - Map the following terms. You may add terms if you...Ch. 19 - Define, compare, and contrast the items in the...Ch. 19 - What are the advantages of a kidney that filters a...Ch. 19 - Prob. 18RQCh. 19 - Diagram the micturition reflex. How is this reflex...Ch. 19 - Antimuscarinic drugs are the accepted treatment...Ch. 19 - Draw a section of renal tubule epithelium showing...Ch. 19 - Prob. 22RQCh. 19 - Read the box on hemodialysis on p. 603 and see if...Ch. 19 - Graphing question: You are given a chemical Z and...Ch. 19 - Prob. 25RQCh. 19 - Prob. 26RQCh. 19 - Dwight was competing for a spot on the Olympic...Ch. 19 - You are a physiologist taking part in an...Ch. 19 - If 140 liters of plasma are filtered in a day, and...
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- Explain the role each of the following plays in GFR regulation: Intrinsic control: Renal autoregulation Myogenic mechanism Tubuloglomerular feedback mechanism Extrinsic control: neural and hormonal mechanism Sympathetic nervous system controls Renin-Angiotensin-Aldosterone mechanismarrow_forwardGiven: For urea, the rate of excretion equals to the GFR times the urea concentration in plasma. (A) If the urea concentration in plasma is 4.5 mmol/l, what GFR (in l/day) would correspond to an excretion rate of 450 mmol/day. (B) If the urea clearance is 70 ml/min and the GFR is 125 ml/min, what fraction of urea is being reabsorbed. (answer A and B)arrow_forwardWhich of the pressures that determine NFP is regulated by both intrinsic and extrinsic controls of GFR?arrow_forward
- Propose several ways to decrease the GFR.arrow_forwardIf the rate of urine formation is 2 ml/min, the urine inulin concentration is 25 mg/ml, and the plasma inulin concentration 0.5 mg/ml, then the GFR is 6.25 mL/min None of the choices are correct. (c) 0.04 mL/min D) 100 mL/min E) more data is needed to calculate the GFRarrow_forwardExplain the importance of regulating GFR. What is the average GFR of a healthy adult in L/min? Describe what happens with GFR as blood pressure increases.arrow_forward
- What is the minimal amount of urine per day that needs to be produced to eliminate waste products and how is it calculated?arrow_forwardIf the Tm for a particular amino acid is 220 mg/100 ml and the concentration of that amino acid in the blood is 130 mg/100 ml, the amino acid will ________. A) not appear in the urine because it is too large to be filtered B) be actively secreted into the filtrate C) be completely reabsorbed by the tubule cellsarrow_forwardWhy is creatinine excretion used to estimate the completeness of a 24-hour urine collection and as a basis for normalizing urinary concentrations of various metabolites and estimating the lean body mass of individuals?arrow_forward
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