Atrial Natriuretic Peptide helps to reduce overall blood pressure in a variety of ways. One way is by increasing Glomerular Filtration Rate. a. Why/how would increasing GFR cause decreased blood pressure? b. To increase GFR, would Atrial Natriuretic Peptide cause constriction or dilation of afferent arterioles at the kidneys? The efferent arterioles

Atrial Natriuretic Peptide helps to reduce overall blood pressure in a variety of ways. One way is by increasing Glomerular Filtration Rate. a. Why/how would increasing GFR cause decreased blood pressure? b. To increase GFR, would Atrial Natriuretic Peptide cause constriction or dilation of afferent arterioles at the kidneys? The efferent arterioles

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter14: The Urinary System

Section: Chapter Questions

Problem 1SQE

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Glomerular filtration can be increased by which of the following? A. Increasing blood flow via afferent arteriole B. Decreasing blood flow via afferent arteriole C. Decreasing arterial blood pressure D. Increasing blood flow via efferent arteriole The answer is (A) Increasing blood flow via afferent arteriole. Please explain why it is not the other options (B,C,D)
Fred was diagnosed 6 months ago with liver cancer. His liver is no longer able to make the necessary amount of proteins needed by the body. What effect, if any, would this have on the net glomerular filtration rate? (Hint, decide which of the 3 forces contributing to the net filtration rate is affected. Then adjust numbers in the equation to determine if there is an increase, decrease, or no change to the net filtration rate). Group of answer choices A) Blood colloid osmotic pressure would be decreased, increasing the net glomerular filtration rate. B) Blood colloid osmotic pressure would be decreased, decreasing the net glomerular filtration rate. C) Capsular hydrostatic pressure would be decreased, increasing the net glomerular filtration rate. D) Capsular hydrostatic pressure would be decreased, decreasing the net glomerular filtration rate. E) There would be no effect on the net glomerular filtration rate.
Which of the following is TRUE about glucose reabsorption in the kidney? a.If an individual does not have diabetes mellitus, 100% of filtered glucose is reabsorbed at the proximal convoluted tubule. b.If an individual has diabetes mellitus, filtered glucose will be present in all the renal tubule. c.Glucose reabsorption along the proximal convoluted tubule uses the sodium glucose secondary active transporter and it is independent of insulin. d.All of the above e.None of the above asap
The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations. For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion Explain how you determined this.
Given: A patient’s GFR (glomerular filtration rate) is 125 ml/min, and his urine is produced at a rate of 1.25 ml/min. (A) By what factor is the inulin concentrate in his urine. (B) The concentration of glucose in his plasma is 5 mmol/l. His renal reabsorption of glucose is completely inhibited. What would be the concentration of glucose in his urine? (answer parts a and b)
Drugs that increase urine flow (diuretic drugs) are often employed in the treatment of hypertension (high blood pressure) or other disease states. Three physiological categories of such drugs are ones that (i) function as loop diuretics, (ii) inhibit the action of aldosterone, and (iii) block Na+ channels in the collecting ducts. Explain why each of these categories would be expected to increase Na+ excretion and urine flow.
The Na+-glucose transporters SGLT2 and SGLT1 are located at different levels of the kidney proximal tubule to minimize spillover of the glucose into the urine (See diagram attached) a) Consider the Na+-glucose coupling ratios for SGLT2 and SGLT1. Why would localization of SGLT2 in the early proximal tubule and SGLT1 in the late proximal tubule be advantageous? b) The Michaelis constant (Km) for the SGLT2 and SGLT1 transporters are 2 mM and 0.5 mM, respectively. Is SGLT2 or SGLT1 the higher affinity Na+-glucose transporter? d) Dapagliflozin is an SGLT1 inhibitor and commonly prescribed to treat type 2 diabetes. Why would this be of benefit to a diabetes patient?
Which of the following statements is true regarding Renal Function and the filtration of molecules? (this is not the same question as '48') 49. A. Large molecules like Glucose are not filtered into the renal tubules because Glucose is too big. B. Glucose molecules are ultimately secreted into the renal tubules; thát is why Glucose is found in the urine of a normal healthy person. C. Glucose molecules are filtered into the renal tubules but are rapidly reabsorbed; that is why very little glucose is found in the urine of a healthy person. D. Plasma Electrolytes are simply too big to be filtered into the renal tubules; that is why only a small concentration of extracellular electrolytes are is found in the urine of a healthy person.
The presence of either protein or glucose in a urinalysis is abnormal, but these two molecules end up in the urine for different reasons. For each of these molecules, briefly describe where in the urine production process (i.e., glomerular filtration, tubular reabsorption or tubular secretion) the problem occurs, and why it might happen.
Which one of the following statements is false?a. Blood pressure in the glomerular capillaries is greater than the osmotic pressure exerted by proteins in the plasma within the glomerular capillaries.b. If the osmotic pressure exerted by solutes in the peritubular capillaries is greater than the blood pressure in those capillaries, then water will be reabsorbed.c. Endothelial cells in glomerular capillaries are highly permeable, facilitating filtration of fluid into Bowman’s capsule.d. Constriction of the afferent arteriole is likely to reduce the volume of filtrate appearing in Bowman’s capsule.e. The efferent arteriole carries blood from the glomerular capillaries directly to the renal vein.0.5 pointsQuestion 2Your doctor calls with the results of your urinalysis and tells you that they found proteinuria, the presence of abnormal amounts of protein in your urine sample. What could have caused this?a. Infection and inflammation in the kidney.b. Abnormally high concentration of plasma…
All of the following are true about glucose recovery from the tubule fluid, except (choose the incorrect statement): A. All filtered glucose is released in the PCT unless plasma glucose abnormally high B. It is reabsorbed by coupling with Na+ recovery via a sodium glucose cotransporter C. Glucose recovery is made possible by low intracellular Na+ concentrations created by the NaK pump D. The CD recovers any glucose that is not reabsorbed by the PCT nephron loop and DCT this is not and will not be graded
1.8 Which of the following is likely to cause the kidney to change the reabsorption of water and/or NaCl? Select one: a. Drinking 1 L of water in a short period of time. (Assume that you weren't dehydrated.) b. Eating a big bag of salty potato chips. c. Forgetting to drink water all day. d. Exercising vigorously in a very hot environment. e. All of the above