Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 19, Problem 3CS
A couple well informed about the epigenetic effects of nutrition and dietary supplements such as choline and folate decided to take supplements before trying to get pregnant. Their first child was born with hair and eye colors very different from the parents and has been consistently praised by teachers for learning ability and memory. The couple attributes these characteristics to their intake of epigenetic supplements. Now they wish to have another child and have informed their physician that they intend to greatly increase the amount of supplements they take to increase the epigenetic effects in their child. The physician cautioned them that studies available in human trials show no effect of choline on learning and that excess intake of folate during pregnancy may be associated with an increased risk of autism spectrum disorder in the child. The couple is convinced that these studies are not conclusive, and while more research is needed, they intend to pursue their plan of increasing their intake of supplements.
What ethical issues should the physician address with the parents about the use of supplements at high dose levels?
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A couple well informed about the epigenetic effects of nutritionand dietary supplements such as choline and folatedecided to take supplements before trying to get pregnant.Their first child was born with hair and eye colors very differentfrom the parents and has been consistently praised by teachersfor learning ability and memory. The couple attributes these characteristicsto their intake of epigenetic supplements. Now theywish to have another child and have informed their physician thatthey intend to greatly increase the amount of supplements theytake to increase the epigenetic effects in their child. The physiciancautioned them that studies available in human trials showno effect of choline on learning and that excess intake of folateduring pregnancy may be associated with an increased risk ofautism spectrum disorder in the child. The couple is convincedthat these studies are not conclusive, and while more research isneeded, they intend to pursue their plan of increasing their…
A scientist does an experiment in which she removes the offspring of rats from their mother at birth and has her genetics students feed and rear the offspring. Assuming that the students do not lick and groom the baby rats as the mother rats normally do, what long-term behavioral and epigenetic effects would you expect to see in the rats when they grow up?
http://www.letsgethealthy.org/students/games/epigenetics-game/ (Links to an external site.)
For the assignment this week I want you to play this epigenetic game that will show you how your choices (which will be the equivalent of of external factors in someone life) make your genes act differently.
Last week, we learned about biology and race and how these fit together in the formation of biological determinants and social misconceptions.
For this week's discussion, play the game. Discuss with your classmates what happened, and what you have learned about epigenetics and how this changes your understanding of genetics . How do epigenetic changes and epigenetic mechanisms in general influence health, our concepts of race, and inequality?
Chapter 19 Solutions
Concepts of Genetics (12th Edition)
Ch. 19 - Although histone modifications can activate or...Ch. 19 - Prob. 2NSTCh. 19 - Prob. 1CSCh. 19 - Prob. 2CSCh. 19 - A couple well informed about the epigenetic...Ch. 19 - Prob. 1PDQCh. 19 - Prob. 2PDQCh. 19 - Prob. 3PDQCh. 19 - Prob. 4PDQCh. 19 - Prob. 5PDQ
Ch. 19 - Prob. 6PDQCh. 19 - Prob. 7PDQCh. 19 - Prob. 8PDQCh. 19 - Prob. 9PDQCh. 19 - Prob. 10PDQCh. 19 - What are the functions of IncRNAs in epigenetic...Ch. 19 - Prob. 12PDQCh. 19 - What are the differences and similarities among...Ch. 19 - Prob. 14PDQCh. 19 - Prob. 15PDQCh. 19 - Should fertility clinics be required by law to...Ch. 19 - Prob. 17PDQCh. 19 - Prob. 18PDQCh. 19 - A developmental disorder in humans called spina...Ch. 19 - Prob. 20PDQCh. 19 - PraderWilli syndrome (PWS) is a genetic disorder...Ch. 19 - Prob. 22ESPCh. 19 - Prob. 23ESPCh. 19 - Methylation of H3K9 by itself silences genes, but...
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- Why is it difficult to study whether a trait is due to epigenetic changes or due to something else? (Hint: What are the other things that may cause disease?) (Minimum of 2 complete sentences.)arrow_forwardEpigenetics is a HUGE new field in understanding health factors that are transmitted from generation to generation beyond simple genetic inheritance. For example: epigenetic factors contribute to the onset of disease by triggering underlying genetic information. What do you think about that?arrow_forwardhttps://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ In what way do the brown and yellow mice shown in the video differ?Why is this so?arrow_forward
- 1) using at least one named example discuss the implication of allelic heterogeneity in single gene disorder for the presentation and progession of the disorder and its treatment 2) discuss the importance of understanding epigenetics in improving people healtharrow_forwardhttps://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ Explain how two genetically identical twins are not really identical.arrow_forwardAn epigenetic study of maternal care in mice was used to study transgenerational epigenetic inheritance. This study found that increased maternal care during childhood resulted in lower stress levels as adults and decreased maternal care with their own offspring. Increased maternal care during childhood resulted in lower stress levels as adults and increased maternal care with their own offspring. Increased maternal care during childhood resulted in higher stress levels as adults and decreased maternal care with their own offspring. Increased maternal care during childhood resulted in higher stress levels as adults and increased maternal care with their own offspring.arrow_forward
- What evidence suggests that differences in monozygotic twins may be caused by epigenetic effects?arrow_forwardEpigenetics has been described as “inheritance, but not as we know it.” Do you think this is a good definition? Why or why not?arrow_forwardDefine epigenetics. Are all epigenetic changes passed from parentto offspring? Explain.arrow_forward
- Describe a potential strategy for the treatment of epigenetic disease.arrow_forwardTransmission of information that is not contained within the sequence of DNA to daughter cells at cell division is called epigenetic inheritance. true falsearrow_forwardDiscuss the similarities and differences of phenotypic variations that are caused by epigenetic gene regulation versus variation in gene sequences (epigenetics versus genetics).arrow_forward
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