Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 19, Problem 16PDQ
Should fertility clinics be required by law to disclose that some assisted reproductive technologies (ARTs) can result in epigenetic diseases? How would you and your partner balance the risks of ART with the desire to have a child?
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Chapter 19 Solutions
Concepts of Genetics (12th Edition)
Ch. 19 - Although histone modifications can activate or...Ch. 19 - Prob. 2NSTCh. 19 - Prob. 1CSCh. 19 - Prob. 2CSCh. 19 - A couple well informed about the epigenetic...Ch. 19 - Prob. 1PDQCh. 19 - Prob. 2PDQCh. 19 - Prob. 3PDQCh. 19 - Prob. 4PDQCh. 19 - Prob. 5PDQ
Ch. 19 - Prob. 6PDQCh. 19 - Prob. 7PDQCh. 19 - Prob. 8PDQCh. 19 - Prob. 9PDQCh. 19 - Prob. 10PDQCh. 19 - What are the functions of IncRNAs in epigenetic...Ch. 19 - Prob. 12PDQCh. 19 - What are the differences and similarities among...Ch. 19 - Prob. 14PDQCh. 19 - Prob. 15PDQCh. 19 - Should fertility clinics be required by law to...Ch. 19 - Prob. 17PDQCh. 19 - Prob. 18PDQCh. 19 - A developmental disorder in humans called spina...Ch. 19 - Prob. 20PDQCh. 19 - PraderWilli syndrome (PWS) is a genetic disorder...Ch. 19 - Prob. 22ESPCh. 19 - Prob. 23ESPCh. 19 - Methylation of H3K9 by itself silences genes, but...
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- Should fertility clinics be required to disclose all the risks of ART to couples seeking fertility treatments? Are state and/or federal laws the best way to achieve this?arrow_forwardJan is concerned about using ART. She wants to be the genetic mother and have Darryl be the genetic father of any children they have. What methods of ART would you recommend to this couple? Jan, a 32-year-old woman, and her husband, Darryl, have been married for 7 years. They have attempted to have a baby on several occasions. Five years ago, they had a first-trimester miscarriage, followed by an ectopic pregnancy later the same year. Jan continued to see her OB/GYN physician for infertility problems but was very dissatisfied with the response. After four miscarriages, she went to see a fertility specialist, who diagnosed her with severe endometriosis and polycystic ovarian disease (detected by hormone studies). The infertility physician explained that these two conditions were hampering her ability to become pregnant and thus making her infertile. She referred Jan to a genetic counselor. At the appointment, the counselor explained to Jan that one form of endometriosis (MIM 131200) can be a genetic disorder, and that polycystic ovarian disease can also be a genetic disorder (MIM 184700) and is one of the most common reproductive disorders among women. The counselor recommended that a detailed family history of both Jan and Darryl would help establish whether Jans problems have a genetic component and whether any of her potential daughters would be at risk for one or both of these disorders. In the meantime, Jan is taking hormones, and she and Darryl are considering alternative modes of reproduction. Using the information in Figure 16.4, explain the reproductive options that are open to Jan and Darryl.arrow_forwardCan We Talk About Sex? Abstract: A three–year–old female undergoes elective inguinal hernia repair and unexpectedly is found to have testes in the hernia sacs. A recommendation is made not to disclose the patient’s genotype to her mother. This case study addresses the ethical conflict of whether to disclose the patient’s male genotype to the parent that has been raising the child as female. This case highlights the ethical risks and potential consequences later in life of not disclosing a patient’s CAIS diagnosis and treatment. Conversely, what would the consequences be for disclosing?arrow_forward
- What is the karyotype for women who have an extra X-chromosome? Discuss all the ways you can test for this abnormality.arrow_forwardWhat is the definition implantation?arrow_forwardA couple contemplating a pregnancy are in today for an appointment at a genetic counselling clinic to identify and interpret their risk of an inherited disorder. The nurse explains during teaching that all the following are characteristic features of fragile X chromosome of a 3-year-old male child EXCEPT: a. Macroorchidism b. Autistic behavior c. Intellectual disability d. Characteristic facial features e. Hyperextensible finger jointsarrow_forward
- Mrs. Xexy Lucero, G0, who is planning to become pregnant tells Nurse Sasha, "I am scared. My brother Zanjo, who was born 2 years after I was, died a month after he was born. My mother says that he had a very serious genetic defect. I don't know what to do." Which of the following responses are appropriate for Nurse Zasha to make? (Select all that apply). a. I Think your mother should make an appointment to meet with your obstetrician. I'm sure she knows a lot more about your brother's illness than she is telling you." b. There are a number of tests that can be performed during your pregnancy tO Screen the baby for genetic diseases." c. lt is almost impossible to figure out what happened way back then, but l'm sure everything will be fine with your baby." d. Do you think your mother would allow your brother's body to be unearthed so that it could be tested for the genetic disease? e. I will discuss your concerns with your Obstetrician. I am sure your doctor will refer you to agenetic…arrow_forwardA devout Catholic couple is in a dilemma whether to opt for homologous IVF or not after being married for 12 years and still no child of their own. They subjected themselves to infertility work up but to no avail. They tried many sexual activity techniques hoping for a baby but to their dismay none was given to them. They sometimes argue and blame one another because of this problem. The wife is so eager to have a child. The husband is okay with or without a child. They visited the wife’s obstetrician who was responsible also for their infertility work up and suggested if they really want to have a child, they would go for IVF. They have options: they can have their own egg and sperm or they could find a third party for surrogate. They really wanted to have a child of their own and so they come to you for advice since they were thinking to undergo homologous IVF. What is your advice to this Catholic couple?arrow_forwardListen Two parents who do not have a condition have a daughter who has the condition. Which of the following possibilities can be eliminated as inheritance pattern for this condition? a) The condition is autosomal dominant O O c) The condition is sex linked recessive b) The condition is sex linked dominant d) All of the above can be eliminatedarrow_forward
- what is the perspective on the stem cell debate regarding donation of surplus embryos to couples for “embryo adoption.”arrow_forward(1) What is the karyotype for men who have an extra Y chromosome? Discuss all the ways you can test for this abnormality. (2) What is the karyotype for women who have an extra X-chromosome? Discuss all the ways you can test for this abnormality.arrow_forwardIn vitro fertilization (IVF) is a common assistive reproductive technology for couples who are struggling to conceive naturally; however, the success rate of IVF is, at best, about 55%. Researchers seeking to improve the success of IVF need to observe the interaction between sperm and eggs in order to better understand the factors that favour fertilization. Obviously, larger sperm and eggs would be easier to observe, even with the aid of microscopy. On this basis, which of the following vertebrate groups might be a good model for studying IVF because they are likely contain species with large sperm and eggs? Group of answer choices a) fish b) amphibians c) reptiles d) birds e) mammalsarrow_forward
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