(a)
Interpretation:
The product of the claisen condensation of ethyl phenylacetate in the presence of sodium ethoxide ion has to be shown.
Concept introduction:
When two molecules of an ester undergo condensation, then it is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.
A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.
The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.
(b)
Interpretation:
The product of the claisen condensation of methyl hexanoate in the preesnce of sodium ethoxide ion has to be shown.
Concept introduction:
When two molecules of an ester undergo condensation, then it is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.
A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.
The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.
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Chapter 19 Solutions
Organic Chemistry
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- When trichloroacetaldehyde is dissolved in water, almost all of it is converted to the hydrate. Chloral hydrate, the product of the reaction, is a sedative that can be lethal. A cocktail laced with it is known—in detective novels, at least—as a “Mickey Finn.” Explain why an aqueous solution of trichloroacetaldehyde is almost all hydrate.arrow_forwardRank the A,B,C,D compound corresponding to their increasing basicity.arrow_forwardProvide an explanation (in detail) on how base catalysts speed up nucleophilic reactions of carbonyl compounds.arrow_forward
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