Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 18, Problem 18PDQ
Summary Introduction
To determine: The ways by which mRNAs are stored in a translationally inactive state.
Introduction: Translation is the process of protein biosynthesis. The genetic code carried by mRNA is decoded to produce the specific sequence of amino acids, which further form a polypeptide chain.
Summary Introduction
To determine: The ways by which translation of stored mRNAs can be stimulated.
Introduction: mRNA is a type of RNA molecule that transfers the genetic information from DNA to the ribosome. The ribosome is the site of protein synthesis. Therefore, a chain of the polypeptide is formed on the ribosome.
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Chapter 18 Solutions
Concepts of Genetics (12th Edition)
Ch. 18 - Some mutations in the tra gene of Drosophila cause...Ch. 18 - Some scientists use the analogy that the...Ch. 18 - Consider the example that actin mRNA localization...Ch. 18 - What is alternative splicing, where does it occur,...Ch. 18 - What role might the expanded tri- and...Ch. 18 - DM1 is characterized by a phenomenon known as...Ch. 18 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 18 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 18 - List three types of alternative splicing patterns...Ch. 18 - Consider the CT/CGRP example of alternative...
Ch. 18 - Explain how the use of alternative promoters and...Ch. 18 - Explain how a tissue-specific RNA-binding protein...Ch. 18 - The regulation of mRNA decay relies heavily upon...Ch. 18 - Nonsense-mediated decay is an mRNA surveillance...Ch. 18 - AU-rich elements (AREs) are cis-elements in mRNAs...Ch. 18 - What are processing bodies (P bodies), and what...Ch. 18 - In 1998, future Nobel laureates Andrew Fire and...Ch. 18 - Present an overview of RNA interference (RNAi)....Ch. 18 - RNAi may be directed by small interfering RNAs...Ch. 18 - Prob. 14PDQCh. 18 - In principle, RNAi may be used to fight viral...Ch. 18 - Prob. 16PDQCh. 18 - Prob. 17PDQCh. 18 - Prob. 18PDQCh. 18 - Prob. 19PDQCh. 18 - How is it possible that a given mRNA in a cell is...Ch. 18 - Prob. 21PDQCh. 18 - Prob. 22PDQCh. 18 - Prob. 23PDQCh. 18 - Prob. 24ESPCh. 18 - Prob. 25ESPCh. 18 - Mutations in the low-density lipoprotein receptor...Ch. 18 - RNA helicases are a class of proteins that bind...Ch. 18 - While miRNA response elements (MREs) may be...Ch. 18 - RNAi is currently being tested as a therapeutic...Ch. 18 - The localization and translational control of...Ch. 18 - Explain how the expression of a single gene can be...
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- What is the "genetic code" and what aspect of post translational modification virtually mandates that "genetic code" applies to mRNA rather than DNA?arrow_forwardIn a eukaryotic cell, where does transcription occur? Where does translation occur?arrow_forwardDefine, explain, and differentiate between, the processes of transcription and translation. What enzymes or sub-cellular structures are responsible for carrying out these processes?arrow_forward
- What are the differences of initation, elongation and termination of transcription and translation of prokaryotes and eukaryotes?arrow_forwardHow would a null mutation in the guanylyl transferase gene affect overall mRNA stability in eukaryotic cells?arrow_forwardWhat are eukaryotic translation initiation factors (eIFs)arrow_forward
- How do cells make a mature mRNA from a gene whose coding sequences are interrupted by introns?arrow_forwardDescribe how mature messenger ribonucleic acids (MRNAS) are post-transcriptionally processed in the nucleus before they are transported to the cytoplasm of a eukaryotic cell.arrow_forwardDescribe the various post-transcriptional and post-translational modifications that occur during the transition from pre-mRNA to mature protein.arrow_forward
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