Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 16, Problem 27P
Interpretation Introduction

Interpretation:

The deficiency of steroid 21-hydroxylase leads to excessive production of sex steroids (androgens and estrogens). Explain the reason.

Concept introduction:

Congenital adrenal hyperplasia is an autosomal recessive disorder which is caused by the deficiency of one of the enzymes needed for the biosynthesis of cortisol in the adrenal glands. 21-hydroxylase deficiency is one of the most common reasons of congenital adrenal hyperplasia.

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