Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 16, Problem 13P
Interpretation Introduction

Interpretation:

The number of tritium atoms incorporated into palmitate during the fatty acid synthesis carried out in vitro with the labeled substrate should be determined.

Concept introduction:

The given structure is tritium labeled malonyl-CoA. The fatty acid synthesis is being carried out using malonyl-CoA as initial substrate. Palmitic acid is a saturated fatty acid containing 16 carbons. A sequence involving seven enzyme catalyzed reactions converts two carbon units to four carbon units.

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