Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 14.3, Problem 2COMQ
During attenuation, when tryptophan levels are high, the ________ stem-loop forms and transcription _________ the trpL gene.
a. 1–2, ends just past
b. 3–4, ends just past
c. 1–2, continues beyond
d. 3–4, continues beyond
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E. coli has five genes that code for enzymes that make tryptophan. These genes
are regulated by a single promoter and transcribed as one long gene. The
presence of tryptophan shut down the production of tryptophan by the cell by
binding to the repressor. This changes the repressors shape allowing it to bind to
DNA operator, blocking RNA polymerase and cutting off the production of
tryptophan. a. Describe what woud happen to the operon if some of the cells
had a mutation on the repressor, not allowing it to bind with tryptophan. The
repressor is described as an allosteric protein. What does this mean? b. Does the
tryptophan model demonstrate an inducible or repressible operon? What is your
evidence? *
E. coli has five genes that code for enzymes that make tryptophan. These genes
are regulated by a single promoter and transcribed as one long gene. The
presence of tryptophan shut down the production of tryptophan by the cell by
binding to the repressor. This changes the repressors shape allowing it to bind to
DNA operator, blocking RNA polymerase and cutting off the production of
tryptophan. a. Describe what would happen to the operon if some of the cells
had a mutation on the repressor, not allowing it to bind with tryptophan. The
repressor is described as an allosteric protein. What does this mean? b. Does the
tryptophan model demonstrate an inducible or repressible operon? What is your
evidence?*
This data shows the efficacy of different treatments on the survival rates of patients with glioblastomas, as well as methylated, and on methylated MGMT promoters.
A. Explain the trends in the figure
B. Relate MGMT methylation to the central dogma/flow of genetic information, and how genes are expressed. 
Chapter 14 Solutions
Genetics: Analysis and Principles
Ch. 14.1 - 1. A repressor is a __________ that _________...Ch. 14.1 - 2. Which of the following combinations will cause...Ch. 14.2 - 1. What is an operon?
a. A site in the DNA where...Ch. 14.2 - The binding of _______ to lac repressor causes lac...Ch. 14.2 - Prob. 3COMQCh. 14.2 - How does exposing an E. coli cell to glucose...Ch. 14.3 - When tryptophan binds to trp repressor, this...Ch. 14.3 - During attenuation, when tryptophan levels are...Ch. 14.3 - Operons involved with the biosynthesis of...Ch. 14.4 - 1. Translation can be regulated by
a....
Ch. 14.4 - Prob. 2COMQCh. 14.5 - 1. For a riboswitch that controls transcription,...Ch. 14 - 1. What is the difference between a constitutive...Ch. 14 - In general, why is it important to regulate genes?...Ch. 14 - Prob. 3CONQCh. 14 - Transcriptional regulation often involves a...Ch. 14 - An operon is repressible-a small effector molecule...Ch. 14 - Prob. 6CONQCh. 14 - 7. What is enzyme adaptation? From a genetic point...Ch. 14 - Prob. 8CONQCh. 14 - Prob. 9CONQCh. 14 - Prob. 10CONQCh. 14 - Mutations may have an effect on the expression of...Ch. 14 - 12. Would a mutation that inactivated lac...Ch. 14 - Prob. 13CONQCh. 14 - 14. As shown in Figure 14.12, four regions within...Ch. 14 - 15. As described in Chapter 13, enzymes known as...Ch. 14 - 16. The combination of a 3–4 stem-loop and a...Ch. 14 - 17. Mutations in tRNA genes can create tRNAs that...Ch. 14 - Prob. 18CONQCh. 14 - Prob. 19CONQCh. 14 - A species of bacteria can synthesize the amino...Ch. 14 - 21. Using three examples, describe how allosteric...Ch. 14 - How are the actions of lac repressor and trp...Ch. 14 - 23. Transcriptional repressor proteins (e.g., lac...Ch. 14 - Answer the following questions that pertain to the...Ch. 14 - Chapter 21 describes a blotting method known as...Ch. 14 - As described in experimental question E2 and also...Ch. 14 - Prob. 4EQCh. 14 - Explain how the data shown in Figure 14.9 indicate...Ch. 14 - Prob. 6EQCh. 14 - Lets suppose you have isolated a mutant strain of...Ch. 14 - Prob. 1QSDCCh. 14 - Prob. 2QSDC
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